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Mouse Anti-POU3F1 Recombinant Antibody (CBXO-0312) (CBMAB-O0292-CQ)


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Summary

Host Animal
Mouse
Specificity
Human
Clone
CBXO-0312
Antibody Isotype
IgG
Application
WB, IP, IF, ELISA

Basic Information

Specificity
Human
Antibody Isotype
IgG
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
POU domain, class 3, transcription factor 1
Introduction
POU3F1 may act as a transcriptional regulator of gene expression during Schwann cell differentiation and myelination.
Entrez Gene ID
5453
UniProt ID
Q03052
Alternative Names
Otf6; Scip; Oct-6; Tst-1
Function
Transcription factor that binds to the octamer motif (5'-ATTTGCAT-3') (By similarity).
Acts as a transcriptional activator when binding cooperatively with SOX4, SOX11, or SOX12 to gene promoters (By similarity).
Acts as a transcriptional repressor of myelin-specific genes (By similarity).
Biological Process
Axon ensheathmentManual Assertion Based On ExperimentTAS:ProtInc
Forebrain developmentIEA:Ensembl
Keratinocyte differentiationIEA:Ensembl
Myelination in peripheral nervous systemIEA:Ensembl
Positive regulation of gene expressionISS:UniProtKB
Positive regulation of transcription, DNA-templatedISS:UniProtKB
Regulation of transcription by RNA polymerase IIManual Assertion Based On ExperimentIBA:GO_Central
Cellular Location
Nucleus
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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