PROM2

PROM2 is a member of the prominin family of pentaspan membrane glycoproteins. The encoded protein localizes to basal epithelial cells and may be involved in the organization of plasma membrane microdomains.

Prominin 2

Negative regulation of caveolin-mediated endocytosisManual Assertion Based On ExperimentIDA:UniProtKB
Negative regulation of pinocytosisManual Assertion Based On ExperimentIDA:UniProtKB
Positive regulation of cell projection organizationManual Assertion Based On ExperimentIDA:UniProtKB
Positive regulation of protein phosphorylationManual Assertion Based On ExperimentIDA:UniProtKB
Regulation of GTPase activityManual Assertion Based On ExperimentIDA:UniProtKB

Apical cell membrane
Basolateral cell membrane
Cell projection, microvillus membrane
Cell projection, cilium membrane
Colocalizes with PROM1. Associates with membrane in a cholesterol-dependent manner. Localizes to the apical and basolateral membranes of epithelial cells (By similarity).

Extracellular: 27-106
Helical: 107-127
Cytoplasmic: 128-153
Helical: 154-174
Extracellular: 175-426
Helical: 427-447
Cytoplasmic: 448-472
Helical: 473-493
Extracellular: 494-779
Helical: 780-800
Cytoplasmic: 801-834

Glycosylated.