PROM2

PROM2 is a member of the prominin family of pentaspan membrane glycoproteins. The encoded protein localizes to basal epithelial cells and may be involved in the organization of plasma membrane microdomains.
Full Name
Prominin 2
Biological Process
Negative regulation of caveolin-mediated endocytosisManual Assertion Based On ExperimentIDA:UniProtKB
Negative regulation of pinocytosisManual Assertion Based On ExperimentIDA:UniProtKB
Positive regulation of cell projection organizationManual Assertion Based On ExperimentIDA:UniProtKB
Positive regulation of protein phosphorylationManual Assertion Based On ExperimentIDA:UniProtKB
Regulation of GTPase activityManual Assertion Based On ExperimentIDA:UniProtKB
Cellular Location
Apical cell membrane
Basolateral cell membrane
Cell projection, microvillus membrane
Cell projection, cilium membrane
Colocalizes with PROM1. Associates with membrane in a cholesterol-dependent manner. Localizes to the apical and basolateral membranes of epithelial cells (By similarity).
Topology
Extracellular: 27-106
Helical: 107-127
Cytoplasmic: 128-153
Helical: 154-174
Extracellular: 175-426
Helical: 427-447
Cytoplasmic: 448-472
Helical: 473-493
Extracellular: 494-779
Helical: 780-800
Cytoplasmic: 801-834
PTM
Glycosylated.
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Anti-PROM2 antibodies

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Mouse Anti-PROM2 Recombinant Antibody (5E5) (CBMAB-P2992-YC)

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Target: PROM2
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: 5E5
Application*: WB, IP
Datasheet SDS

Mouse Anti-PROM2 Recombinant Antibody (244029) (CBMAB-P2991-YC)

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Target: PROM2
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: 244029
Application*: F
Datasheet SDS

Mouse Anti-PROM2 Recombinant Antibody (13A9) (CBMAB-P2990-YC)

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Target: PROM2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 13A9
Application*: IF, P, WB
Datasheet SDS
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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IGImmunochromatography
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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