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Mouse Anti-PROM2 Recombinant Antibody (13A9) (CBMAB-P2990-YC)

Provided herein is a Mouse monoclonal antibody against Human Prominin 2. The antibody can be used for immunoassay techniques, such as IF, IHC-P, WB.
See all PROM2 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
13A9
Antibody Isotype
IgG1
Application
IF, IHC-P, WB

Basic Information

Immunogen
Protein expressed in 293T cell transfected with human PROM2 expression vector
Specificity
Human
Antibody Isotype
IgG1
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at-20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
Prominin 2
Introduction
PROM2 is a member of the prominin family of pentaspan membrane glycoproteins. The encoded protein localizes to basal epithelial cells and may be involved in the organization of plasma membrane microdomains.
Entrez Gene ID
150696
UniProt ID
Q8N271
Alternative Names
PROML2
Biological Process
Negative regulation of caveolin-mediated endocytosisManual Assertion Based On ExperimentIDA:UniProtKB
Negative regulation of pinocytosisManual Assertion Based On ExperimentIDA:UniProtKB
Positive regulation of cell projection organizationManual Assertion Based On ExperimentIDA:UniProtKB
Positive regulation of protein phosphorylationManual Assertion Based On ExperimentIDA:UniProtKB
Regulation of GTPase activityManual Assertion Based On ExperimentIDA:UniProtKB
Cellular Location
Apical cell membrane
Basolateral cell membrane
Cell projection, microvillus membrane
Cell projection, cilium membrane
Colocalizes with PROM1. Associates with membrane in a cholesterol-dependent manner. Localizes to the apical and basolateral membranes of epithelial cells (By similarity).
Topology
Extracellular: 27-106
Helical: 107-127
Cytoplasmic: 128-153
Helical: 154-174
Extracellular: 175-426
Helical: 427-447
Cytoplasmic: 448-472
Helical: 473-493
Extracellular: 494-779
Helical: 780-800
Cytoplasmic: 801-834
PTM
Glycosylated.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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