RAB20
RAB20 (RAB20, Member RAS Oncogene Family) is a Protein Coding gene. Among its related pathways are Metabolism of proteins and RAB geranylgeranylation. Gene Ontology (GO) annotations related to this gene include GTP binding and GTPase activity. An important paralog of this gene is RAB5C.
Full Name
RAB20, Member RAS Oncogene Family
Function
Plays a role in apical endocytosis/recycling. Plays a role in the maturation and acidification of phagosomes that engulf pathogens, such as S.aureus and M.tuberculosis. Plays a role in the fusion of phagosomes with lysosomes.
Biological Process
Biological Process cellular response to interferon-gammaIEA:Ensembl
Biological Process intracellular protein transportManual Assertion Based On ExperimentIBA:GO_Central
Biological Process phagosome acidificationManual Assertion Based On ExperimentIMP:UniProtKB
Biological Process phagosome-lysosome fusionManual Assertion Based On ExperimentIMP:UniProtKB
Biological Process intracellular protein transportManual Assertion Based On ExperimentIBA:GO_Central
Biological Process phagosome acidificationManual Assertion Based On ExperimentIMP:UniProtKB
Biological Process phagosome-lysosome fusionManual Assertion Based On ExperimentIMP:UniProtKB
Cellular Location
Golgi apparatus
Cytoplasmic vesicle, phagosome
Cytoplasmic vesicle, phagosome membrane
Highly enriched on apical endocytic structures in polarized epithelial cells of kidney proximal tubules (By similarity).
Recruited to phagosomes containing S.aureus or M.tuberculosis (PubMed:21255211).
Cytoplasmic vesicle, phagosome
Cytoplasmic vesicle, phagosome membrane
Highly enriched on apical endocytic structures in polarized epithelial cells of kidney proximal tubules (By similarity).
Recruited to phagosomes containing S.aureus or M.tuberculosis (PubMed:21255211).
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Anti-RAB20 antibodies
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Target: RAB20
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 1F1
Application*: WB
Target: RAB20
Host: Mouse
Specificity: Human
Clone: 1694CT210.218.54
Application*: F
Target: RAB20
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: 1694CT210.142.16
Application*: WB
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For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
- AActivation
- AGAgonist
- APApoptosis
- BBlocking
- BABioassay
- BIBioimaging
- CImmunohistochemistry-Frozen Sections
- CIChromatin Immunoprecipitation
- CTCytotoxicity
- CSCostimulation
- DDepletion
- DBDot Blot
- EELISA
- ECELISA(Cap)
- EDELISA(Det)
- ESELISpot
- EMElectron Microscopy
- FFlow Cytometry
- FNFunction Assay
- GSGel Supershift
- IInhibition
- IAEnzyme Immunoassay
- ICImmunocytochemistry
- IDImmunodiffusion
- IEImmunoelectrophoresis
- IFImmunofluorescence
- IGImmunochromatography
- IHImmunohistochemistry
- IMImmunomicroscopy
- IOImmunoassay
- IPImmunoprecipitation
- ISIntracellular Staining for Flow Cytometry
- LALuminex Assay
- LFLateral Flow Immunoassay
- MMicroarray
- MCMass Cytometry/CyTOF
- MDMeDIP
- MSElectrophoretic Mobility Shift Assay
- NNeutralization
- PImmunohistologyp-Paraffin Sections
- PAPeptide Array
- PEPeptide ELISA
- PLProximity Ligation Assay
- RRadioimmunoassay
- SStimulation
- SESandwich ELISA
- SHIn situ hybridization
- TCTissue Culture
- WBWestern Blot
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