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Mouse Anti-RAB20 Recombinant Antibody (1F1) (CBMAB-R0739-CN)

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Summary

Host Animal
Mouse
Specificity
Human
Clone
1F1
Antibody Isotype
IgG1
Application
WB

Basic Information

Specificity
Human
Antibody Isotype
IgG1
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Target

Full Name
RAB20, Member RAS Oncogene Family
Introduction
RAB20 (RAB20, Member RAS Oncogene Family) is a Protein Coding gene. Among its related pathways are Metabolism of proteins and RAB geranylgeranylation. Gene Ontology (GO) annotations related to this gene include GTP binding and GTPase activity. An important paralog of this gene is RAB5C.
Entrez Gene ID
UniProt ID
Alternative Names
RAB20, Member RAS Oncogene Family;
Function
Plays a role in apical endocytosis/recycling. Plays a role in the maturation and acidification of phagosomes that engulf pathogens, such as S.aureus and M.tuberculosis. Plays a role in the fusion of phagosomes with lysosomes.
Biological Process
Biological Process cellular response to interferon-gammaIEA:Ensembl
Biological Process intracellular protein transportManual Assertion Based On ExperimentIBA:GO_Central
Biological Process phagosome acidificationManual Assertion Based On ExperimentIMP:UniProtKB
Biological Process phagosome-lysosome fusionManual Assertion Based On ExperimentIMP:UniProtKB
Cellular Location
Golgi apparatus
Cytoplasmic vesicle, phagosome
Cytoplasmic vesicle, phagosome membrane
Highly enriched on apical endocytic structures in polarized epithelial cells of kidney proximal tubules (By similarity).
Recruited to phagosomes containing S.aureus or M.tuberculosis (PubMed:21255211).
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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