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RAB25

The protein encoded by this gene is a member of the RAS superfamily of small GTPases. The encoded protein is involved in membrane trafficking and cell survival. This gene has been found to be a tumor suppressor and an oncogene, depending on the context. Two variants, one protein-coding and the other not, have been found for this gene. [provided by RefSeq, Nov 2015]
Full Name
RAB25, Member RAS Oncogene Family
Function
Involved in the regulation of cell survival. Promotes invasive migration of cells in which it functions to localize and maintain integrin alpha-V/beta-1 at the tips of extending pseudopodia (PubMed:17925226).
Involved in the regulation of epithelial morphogenesis through the control of CLDN4 expression and localization at tight junctions (By similarity).
May selectively regulate the apical recycling pathway. Together with MYO5B regulates transcytosis (By similarity).
Biological Process
Biological Process epithelial cell morphogenesisISS:UniProtKB
Biological Process exocytosisManual Assertion Based On ExperimentIBA:GO_Central
Biological Process positive regulation of cell population proliferationManual Assertion Based On ExperimentIDA:UniProtKB
Biological Process positive regulation of epithelial cell migrationManual Assertion Based On ExperimentIMP:UniProtKB
Biological Process protein transportIEA:UniProtKB-KW
Biological Process pseudopodium organizationManual Assertion Based On ExperimentIDA:UniProtKB
Biological Process regulation of vesicle-mediated transportManual Assertion Based On ExperimentIMP:UniProtKB
Biological Process vesicle-mediated transportManual Assertion Based On ExperimentIBA:GO_Central
Cellular Location
Cell membrane
Cell projection, pseudopodium membrane
Cytoplasmic vesicle
Colocalizes with integrin alpha-V/beta-1 in vesicles at the pseudopodial tips.
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Anti-RAB25 antibodies

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Mouse Anti-RAB25 Recombinant Antibody (TS106) (CBMAB-R0771-CN)

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Target: RAB25
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: TS106
Application*: WB
Datasheet SDS

Rabbit Anti-RAB25 Recombinant Antibody (D4P6P) (CBMAB-R0770-CN)

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Target: RAB25
Host: Rabbit
Specificity: Human
Clone: D4P6P
Application*: WB, IP, IF
Datasheet SDS

Rabbit Anti-RAB25 Recombinant Antibody (D3H4N) (CBMAB-R0769-CN)

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Target: RAB25
Host: Rabbit
Specificity: Human
Clone: D3H4N
Application*: WB
Datasheet SDS

Mouse Anti-RAB25 Recombinant Antibody (467657) (CBMAB-R0767-CN)

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Target: RAB25
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: 467657
Application*: WB
Datasheet SDS

Mouse Anti-RAB25 Recombinant Antibody (3F12F3) (CBMAB-R0766-CN)

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Target: RAB25
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: 3F12F3
Application*: WB, IH
Datasheet SDS

Mouse Anti-RAB25 Recombinant Antibody (3F12) (CBMAB-R0765-CN)

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Target: RAB25
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Mouse
Clone: 3F12
Application*: WB, IH, IF
Datasheet SDS

Mouse Anti-RAB25 Recombinant Antibody (13B663) (CBMAB-R0764-CN)

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Target: RAB25
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Mouse
Clone: 13B663
Application*: E, F, IH, WB
Datasheet SDS

Mouse Anti-RAB25 Recombinant Antibody (13B662) (CBMAB-R0763-CN)

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Target: RAB25
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: 13B662
Application*: E, IH, WB
Datasheet SDS

Mouse Anti-RAB25 Recombinant Antibody (11n162) (CBMAB-R0762-CN)

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Target: RAB25
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: 11n162
Application*: WB
Datasheet SDS

Mouse Anti-RAB25 Recombinant Antibody (CBT1081) (V2LY-0625-LY3048)

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Target: RAB25
Host: Mouse
Antibody Isotype: IgG
Specificity: Human, Mouse
Clone: CBT1081
Application*: WB, P, IF, IC, F, E
Datasheet SDS

Mouse Anti-RAB25 Recombinant Antibody (CBT1082) (V2LY-0625-LY3047)

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Target: RAB25
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: CBT1082
Application*: WB, P, IF, E
Datasheet SDS

Mouse Anti-Rab25 Recombinant Antibody (CBT3670) (V2LY-0625-LY2350)

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Target: Rab25
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Mouse
Clone: CBT3670
Application*: WB, IH, IC, F
Datasheet SDS

Mouse Anti-Rab25 Recombinant Antibody (CBT3016) (V2LY-0625-LY2082)

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Target: Rab25
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: CBT3016
Application*: IH
Datasheet SDS
More Infomation
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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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