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RARS

Aminoacyl-tRNA synthetases catalyze the aminoacylation of tRNA by their cognate amino acid. Because of their central role in linking amino acids with nucleotide triplets contained in tRNAs, aminoacyl-tRNA synthetases are thought to be among the first proteins that appeared in evolution. Arginyl-tRNA synthetase belongs to the class-I aminoacyl-tRNA synthetase family. [provided by RefSeq, Jul 2008]
Full Name
Arginyl-TRNA Synthetase
Function
Forms part of a macromolecular complex that catalyzes the attachment of specific amino acids to cognate tRNAs during protein synthesis (PubMed:25288775).
Modulates the secretion of AIMP1 and may be involved in generation of the inflammatory cytokine EMAP2 from AIMP1 (PubMed:17443684).
Biological Process
Biological Process arginyl-tRNA aminoacylationManual Assertion Based On ExperimentIDA:UniProtKB
Biological Process tRNA aminoacylation for protein translationTAS:Reactome
Cellular Location
Cytoplasm
Cytoplasm, cytosol
Involvement in disease
Leukodystrophy, hypomyelinating, 9 (HLD9):
An autosomal recessive neurodegenerative disorder characterized by delayed psychomotor development, severe spasticity, nystagmus, and ataxia associated with diffuse hypomyelination apparent on brain MRI.
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Anti-RARS antibodies

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RARS Matched Antibody Pair (967) (APMAB-967LY)

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Target: RARS
Specificity: Human
Datasheet SDS

Mouse Anti-RARS Recombinant Antibody (CBYC-A1033) (CBMAB-A4699-YC)

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Target: RARS
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: CBYC-A1033
Application*: WB, IC, P, C, E
Datasheet SDS

Mouse Anti-RARS Recombinant Antibody (CBYC-A1032) (CBMAB-A4698-YC)

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Target: RARS
Host: Mouse
Antibody Isotype: IgM
Specificity: Human
Clone: CBYC-A1032
Application*: WB, E
Datasheet SDS

Mouse Anti-RARS Recombinant Antibody (V2-82938) (CBMAB-R1446-CN)

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Target: RARS
Host: Mouse
Antibody Isotype: IgG2b, κ
Specificity: Human
Clone: V2-82938
Application*: E, IH, WB
Datasheet SDS
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Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized) Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)

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For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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