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Mouse Anti-RARS Recombinant Antibody (CBYC-A1032) (CBMAB-A4698-YC)

Provided herein is a Mouse monoclonal antibody against Human Arginyl-TRNA Synthetase. The antibody can be used for immunoassay techniques, such as WB, ELISA.
See all RARS antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
CBYC-A1032
Antibody Isotype
IgM
Application
WB, ELISA

Basic Information

Specificity
Human
Antibody Isotype
IgM
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
Arginyl-TRNA Synthetase
Introduction
Aminoacyl-tRNA synthetases catalyze the aminoacylation of tRNA by their cognate amino acid. Because of their central role in linking amino acids with nucleotide triplets contained in tRNAs, aminoacyl-tRNA synthetases are thought to be among the first prot
Entrez Gene ID
5917
UniProt ID
P54136
Alternative Names
2610011N19Rik; 2610037E21Rik; AL033339; AW985894
Function
Forms part of a macromolecular complex that catalyzes the attachment of specific amino acids to cognate tRNAs during protein synthesis (PubMed:25288775).
Modulates the secretion of AIMP1 and may be involved in generation of the inflammatory cytokine EMAP2 from AIMP1 (PubMed:17443684).
Biological Process
Biological Process arginyl-tRNA aminoacylationManual Assertion Based On ExperimentIDA:UniProtKB
Biological Process tRNA aminoacylation for protein translationTAS:Reactome
Cellular Location
Cytoplasm
Cytoplasm, cytosol
Involvement in disease
Leukodystrophy, hypomyelinating, 9 (HLD9):
An autosomal recessive neurodegenerative disorder characterized by delayed psychomotor development, severe spasticity, nystagmus, and ataxia associated with diffuse hypomyelination apparent on brain MRI.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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