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RGS5

This gene encodes a member of the regulators of G protein signaling (RGS) family. The RGS proteins are signal transduction molecules which are involved in the regulation of heterotrimeric G proteins by acting as GTPase activators. This gene is a hypoxia-inducible factor-1 dependent, hypoxia-induced gene which is involved in the induction of endothelial apoptosis. This gene is also one of three genes on chromosome 1q contributing to elevated blood pressure. Alternatively spliced transcript variants have been identified. [provided by RefSeq, Dec 2011]
Full Name
Regulator Of G Protein Signaling 5
Function
Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. Binds to G(i)-alpha and G(o)-alpha, but not to G(s)-alpha (By similarity).
Biological Process
Biological Process G protein-coupled receptor signaling pathwayTAS:Reactome
Biological Process negative regulation of signal transductionIEA:UniProtKB-KW
Biological Process regulation of G protein-coupled receptor signaling pathwayManual Assertion Based On ExperimentTAS:ProtInc
Cellular Location
Isoform 1
Cytoplasm
Membrane
Isoform 2
Cytoplasm
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Anti-RGS5 antibodies

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Mouse Anti-RGS5 Recombinant Antibody (B-4) (CBMAB-R2466-CN)

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Target: RGS5
Host: Mouse
Specificity: Mouse, Rat, Human
Clone: B-4
Application*: WB, IP, IF, E
Datasheet SDS

Mouse Anti-RGS5 Recombinant Antibody (4E12) (CBMAB-R2465-CN)

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Target: RGS5
Host: Mouse
Antibody Isotype: IgG2b, κ
Specificity: Human
Clone: 4E12
Application*: E, WB
Datasheet SDS

Mouse Anti-RGS5 Recombinant Antibody (3H6) (CBMAB-R2464-CN)

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Target: RGS5
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 3H6
Application*: IF, WB
Datasheet SDS

Mouse Anti-RGS5 Recombinant Antibody (1E3) (CBMAB-R2463-CN)

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Target: RGS5
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 1E3
Application*: WB, F
Datasheet SDS

Mouse Anti-RGS5 Recombinant Antibody (1C1) (CBMAB-R2462-CN)

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Target: RGS5
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 1C1
Application*: WB, F, IH, P
Datasheet SDS

RGS5 Matched Antibody Pair (993) (APMAB-993LY)

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Target: RGS5
Specificity: Human
Datasheet SDS

RGS5 Matched Antibody Pair (992) (APMAB-992LY)

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Target: RGS5
Specificity: Human
Datasheet SDS
More Infomation
Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized) Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)

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For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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