Mouse Anti-RGS5 Recombinant Antibody (1C1) (CBMAB-R2462-CN)

Name: Mouse Anti-RGS5 Recombinant Antibody (1C1)
SKU: CBMAB-R2462-CN
Rating: 5 (1 reviews)

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Datasheet

SDS

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Basic Information

Host Animal

Mouse

Clone

1C1

Application

WB, FC, IHC, IHC-P

Immunogen

Full length human recombinant protein of human RGS5 (NP_003608) produced in HEK293T cell

Specificity

Human

Antibody Isotype

IgG1

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

More Infomation

Target

Full Name

Regulator Of G Protein Signaling 5

Introduction

This gene encodes a member of the regulators of G protein signaling (RGS) family. The RGS proteins are signal transduction molecules which are involved in the regulation of heterotrimeric G proteins by acting as GTPase activators. This gene is a hypoxia-inducible factor-1 dependent, hypoxia-induced gene which is involved in the induction of endothelial apoptosis. This gene is also one of three genes on chromosome 1q contributing to elevated blood pressure. Alternatively spliced transcript variants have been identified. [provided by RefSeq, Dec 2011]

Entrez Gene ID

8490

UniProt ID

O15539

Alternative Names

Regulator Of G Protein Signaling 5; Regulator Of G-Protein Signaling 5; Regulator Of G-Protein Signalling 5; MSTP032; MSTP092; MSTP106;

Function

Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. Binds to G(i)-alpha and G(o)-alpha, but not to G(s)-alpha (By similarity).

Biological Process

Biological Process G protein-coupled receptor signaling pathwayTAS:Reactome
Biological Process negative regulation of signal transductionIEA:UniProtKB-KW
Biological Process regulation of G protein-coupled receptor signaling pathwayManual Assertion Based On ExperimentTAS:ProtInc

Cellular Location

Isoform 1
Cytoplasm
Membrane
Isoform 2
Cytoplasm

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme-Linked Immunospot (ELISpot)
Proteogenomics
Other Protocols

Antibody Pairs

RGS5 Matched Antibody Pair (992) (CAT#: APMAB-992LY)

RGS5 Matched Antibody Pair (993) (CAT#: APMAB-993LY)

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RGS5 Matched Antibody Pair (993) (CAT#: APMAB-993LY)

Mouse Anti-RGS5 Recombinant Antibody (B-4) (CAT#: CBMAB-R2466-CN)

Mouse Anti-RGS5 Recombinant Antibody (1E3) (CAT#: CBMAB-R2463-CN)

Mouse Anti-RGS5 Recombinant Antibody (4E12) (CAT#: CBMAB-R2465-CN)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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