Sign in or Register   Sign in or Register
  |  

Mouse Anti-RGS5 Recombinant Antibody (3H6) (CBMAB-R2464-CN)

This product is a Mouse antibody that recognizes RGS5. The antibody 3H6 can be used for immunoassay techniques such as: IF, WB.
See all RGS5 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
3H6
Antibody Isotype
IgG1
Application
IF, WB

Basic Information

Immunogen
A human recombinant protein fragment corresponding to aa. 1-181 of human RGS5 (NP_003608) produced in E. coli
Specificity
Human
Antibody Isotype
IgG1
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Buffer
PBS, pH 7.3, 1% BSA, 50% Glycerol
Preservative
0.02% Sodium azide
Concentration
0.5-1 mg/mL

Target

Full Name
Regulator Of G Protein Signaling 5
Introduction
This gene encodes a member of the regulators of G protein signaling (RGS) family. The RGS proteins are signal transduction molecules which are involved in the regulation of heterotrimeric G proteins by acting as GTPase activators. This gene is a hypoxia-inducible factor-1 dependent, hypoxia-induced gene which is involved in the induction of endothelial apoptosis. This gene is also one of three genes on chromosome 1q contributing to elevated blood pressure. Alternatively spliced transcript variants have been identified. [provided by RefSeq, Dec 2011]
Entrez Gene ID
8490
UniProt ID
O15539
Alternative Names
Regulator Of G Protein Signaling 5; Regulator Of G-Protein Signaling 5; Regulator Of G-Protein Signalling 5; MSTP032; MSTP092; MSTP106;
Function
Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. Binds to G(i)-alpha and G(o)-alpha, but not to G(s)-alpha (By similarity).
Biological Process
Biological Process G protein-coupled receptor signaling pathwayTAS:Reactome
Biological Process negative regulation of signal transductionIEA:UniProtKB-KW
Biological Process regulation of G protein-coupled receptor signaling pathwayManual Assertion Based On ExperimentTAS:ProtInc
Cellular Location
Isoform 1
Cytoplasm
Membrane
Isoform 2
Cytoplasm
Ask a question We look forward to hearing from you.
0 reviews or Q&As

Purchasing FAQs
Technical FAQs

Loading...
Have you used Mouse Anti-RGS5 Recombinant Antibody (3H6)?
Submit a review and get a Coupon or an Amazon gift card. 20% off Coupon $30 eGift Card
Submit a review
Loading...
For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

Online Inquiry

Documents

Contact us

  • Tel: (USA)
  • (UK)
  • Fax:
  • Email:

Submit A Review

Go to
Compare