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RIT2

RIN belongs to the RAS (HRAS; MIM 190020) superfamily of small GTPases (Shao et al., 1999 [PubMed 10545207]).[supplied by OMIM
Full Name
Ras-like without CAAX 2
Function
Binds and exchanges GTP and GDP. Binds and modulates the activation of POU4F1 as gene expression regulator.
Biological Process
Biological Process adenylate cyclase-activating G protein-coupled receptor signaling pathwayIEA:Ensembl
Biological Process chemical synaptic transmissionManual Assertion Based On ExperimentTAS:ProtInc
Biological Process intracellular signal transductionManual Assertion Based On ExperimentIDA:ParkinsonsUK-UCL
Biological Process maintenance of protein location in cellManual Assertion Based On ExperimentIMP:ParkinsonsUK-UCL
Biological Process negative regulation of neuron projection developmentIEA:Ensembl
Biological Process positive regulation of MAPK cascadeISS:ParkinsonsUK-UCL
Biological Process positive regulation of neuron projection developmentManual Assertion Based On ExperimentIGI:ParkinsonsUK-UCL
Biological Process positive regulation of transcription by RNA polymerase IIIEA:Ensembl
Biological Process Ras protein signal transductionISS:ParkinsonsUK-UCL
Biological Process regulation of calcium-mediated signalingISS:ParkinsonsUK-UCL
Biological Process regulation of Cdc42 protein signal transductionISS:ParkinsonsUK-UCL
Biological Process regulation of endocytosisManual Assertion Based On ExperimentIMP:ParkinsonsUK-UCL
Biological Process regulation of protein phosphorylationIEA:Ensembl
Biological Process small GTPase mediated signal transduction1 PublicationNAS:UniProtKB
Cellular Location
Nucleus
Cell membrane
Colocalizes with PLXNB3 at the plasma membrane (PubMed:16122393).
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Anti-RIT2 antibodies

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Mouse Anti-RIT2 Recombinant Antibody (CBCNR-535) (CBMAB-R2777-CN)

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Target: RIT2
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human, Mouse
Clone: CBCNR-535
Application*: WB, P
Datasheet SDS

Mouse Anti-RIT2 Recombinant Antibody (4B5) (CBMAB-R2776-CN)

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Target: RIT2
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: 4B5
Application*: F, IF, WB
Datasheet SDS

Mouse Anti-RIT2 Recombinant Antibody (4A6) (CBMAB-R2775-CN)

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Target: RIT2
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human, Mouse
Clone: 4A6
Application*: WB
Datasheet SDS

Mouse Anti-RIT2 Recombinant Antibody (456313) (CBMAB-R2774-CN)

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Target: RIT2
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: 456313
Application*: WB, IH
Datasheet SDS

Mouse Anti-RIT2 Recombinant Antibody (3F4) (CBMAB-R2773-CN)

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Target: RIT2
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human, Rat, Dog
Clone: 3F4
Application*: WB, F, IH, P
Datasheet SDS

Mouse Anti-RIT2 Recombinant Antibody (3F2) (CBMAB-R2772-CN)

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Target: RIT2
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: 3F2
Application*: E, WB
Datasheet SDS

Mouse Anti-RIT2 Recombinant Antibody (27G2) (CBMAB-R2771-CN)

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Target: RIT2
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: 27G2
Application*: WB, P
Datasheet SDS

Mouse Anti-RIT2 Recombinant Antibody (1G2) (CBMAB-R2770-CN)

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Target: RIT2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 1G2
Application*: WB, F, IF
Datasheet SDS

Mouse Anti-RIT2 Recombinant Antibody (11C49) (CBMAB-R2769-CN)

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Target: RIT2
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: 11C49
Application*: IH, WB
Datasheet SDS
More Infomation
Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized) Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)

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For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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