RIT2

RIN belongs to the RAS (HRAS; MIM 190020) superfamily of small GTPases (Shao et al., 1999 [PubMed 10545207]).[supplied by OMIM

Ras-like without CAAX 2

Binds and exchanges GTP and GDP. Binds and modulates the activation of POU4F1 as gene expression regulator.

Biological Process adenylate cyclase-activating G protein-coupled receptor signaling pathwayIEA:Ensembl
Biological Process chemical synaptic transmissionManual Assertion Based On ExperimentTAS:ProtInc
Biological Process intracellular signal transductionManual Assertion Based On ExperimentIDA:ParkinsonsUK-UCL
Biological Process maintenance of protein location in cellManual Assertion Based On ExperimentIMP:ParkinsonsUK-UCL
Biological Process negative regulation of neuron projection developmentIEA:Ensembl
Biological Process positive regulation of MAPK cascadeISS:ParkinsonsUK-UCL
Biological Process positive regulation of neuron projection developmentManual Assertion Based On ExperimentIGI:ParkinsonsUK-UCL
Biological Process positive regulation of transcription by RNA polymerase IIIEA:Ensembl
Biological Process Ras protein signal transductionISS:ParkinsonsUK-UCL
Biological Process regulation of calcium-mediated signalingISS:ParkinsonsUK-UCL
Biological Process regulation of Cdc42 protein signal transductionISS:ParkinsonsUK-UCL
Biological Process regulation of endocytosisManual Assertion Based On ExperimentIMP:ParkinsonsUK-UCL
Biological Process regulation of protein phosphorylationIEA:Ensembl
Biological Process small GTPase mediated signal transduction1 PublicationNAS:UniProtKB

Nucleus
Cell membrane
Colocalizes with PLXNB3 at the plasma membrane (PubMed:16122393).