Mouse Anti-RIT2 Recombinant Antibody (27G2) (CBMAB-R2771-CN)

Name: Mouse Anti-RIT2 Recombinant Antibody (27G2)
SKU: CBMAB-R2771-CN
Rating: 5 (1 reviews)

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Datasheet

SDS

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Basic Information

Host Animal

Mouse

Clone

27G2

Application

WB, IHC-P

Specificity

Human

Antibody Isotype

IgG2b

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Concentration

1 mg/mL

More Infomation

Target

Full Name

Ras-like without CAAX 2

Introduction

RIN belongs to the RAS (HRAS; MIM 190020) superfamily of small GTPases (Shao et al., 1999 [PubMed 10545207]). [supplied by OMIM, Mar 2008]

Entrez Gene ID

6014

UniProt ID

Q99578

Alternative Names

Ras Like Without CAAX 2; Ras-Like Protein Expressed In Neurons; Ras-Like Without CAAX Protein 2; ROC2; RIN; Ric (Drosophila)-Like, Expressed In Neurons;

Function

Binds and exchanges GTP and GDP. Binds and modulates the activation of POU4F1 as gene expression regulator.

Biological Process

Biological Process adenylate cyclase-activating G protein-coupled receptor signaling pathwayIEA:Ensembl
Biological Process chemical synaptic transmissionManual Assertion Based On ExperimentTAS:ProtInc
Biological Process intracellular signal transductionManual Assertion Based On ExperimentIDA:ParkinsonsUK-UCL
Biological Process maintenance of protein location in cellManual Assertion Based On ExperimentIMP:ParkinsonsUK-UCL
Biological Process negative regulation of neuron projection developmentIEA:Ensembl
Biological Process positive regulation of MAPK cascadeISS:ParkinsonsUK-UCL
Biological Process positive regulation of neuron projection developmentManual Assertion Based On ExperimentIGI:ParkinsonsUK-UCL
Biological Process positive regulation of transcription by RNA polymerase IIIEA:Ensembl
Biological Process Ras protein signal transductionISS:ParkinsonsUK-UCL
Biological Process regulation of calcium-mediated signalingISS:ParkinsonsUK-UCL
Biological Process regulation of Cdc42 protein signal transductionISS:ParkinsonsUK-UCL
Biological Process regulation of endocytosisManual Assertion Based On ExperimentIMP:ParkinsonsUK-UCL
Biological Process regulation of protein phosphorylationIEA:Ensembl
Biological Process small GTPase mediated signal transduction1 PublicationNAS:UniProtKB

Cellular Location

Nucleus
Cell membrane
Colocalizes with PLXNB3 at the plasma membrane (PubMed:16122393).

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme-Linked Immunospot (ELISpot)
Proteogenomics
Other Protocols

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Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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