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Mouse Anti-RIT2 Recombinant Antibody (27G2) (CBMAB-R2771-CN)

This product is a Mouse antibody that recognizes RIT2. The antibody 27G2 can be used for immunoassay techniques such as: WB, IHC-P.
See all RIT2 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
27G2
Antibody Isotype
IgG2b
Application
WB, IHC-P

Basic Information

Specificity
Human
Antibody Isotype
IgG2b
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Concentration
1 mg/mL

Target

Full Name
Ras-like without CAAX 2
Introduction
RIN belongs to the RAS (HRAS; MIM 190020) superfamily of small GTPases (Shao et al., 1999 [PubMed 10545207]). [supplied by OMIM, Mar 2008]
Entrez Gene ID
6014
UniProt ID
Q99578
Alternative Names
Ras Like Without CAAX 2; Ras-Like Protein Expressed In Neurons; Ras-Like Without CAAX Protein 2; ROC2; RIN; Ric (Drosophila)-Like, Expressed In Neurons;
Function
Binds and exchanges GTP and GDP. Binds and modulates the activation of POU4F1 as gene expression regulator.
Biological Process
Biological Process adenylate cyclase-activating G protein-coupled receptor signaling pathwayIEA:Ensembl
Biological Process chemical synaptic transmissionManual Assertion Based On ExperimentTAS:ProtInc
Biological Process intracellular signal transductionManual Assertion Based On ExperimentIDA:ParkinsonsUK-UCL
Biological Process maintenance of protein location in cellManual Assertion Based On ExperimentIMP:ParkinsonsUK-UCL
Biological Process negative regulation of neuron projection developmentIEA:Ensembl
Biological Process positive regulation of MAPK cascadeISS:ParkinsonsUK-UCL
Biological Process positive regulation of neuron projection developmentManual Assertion Based On ExperimentIGI:ParkinsonsUK-UCL
Biological Process positive regulation of transcription by RNA polymerase IIIEA:Ensembl
Biological Process Ras protein signal transductionISS:ParkinsonsUK-UCL
Biological Process regulation of calcium-mediated signalingISS:ParkinsonsUK-UCL
Biological Process regulation of Cdc42 protein signal transductionISS:ParkinsonsUK-UCL
Biological Process regulation of endocytosisManual Assertion Based On ExperimentIMP:ParkinsonsUK-UCL
Biological Process regulation of protein phosphorylationIEA:Ensembl
Biological Process small GTPase mediated signal transduction1 PublicationNAS:UniProtKB
Cellular Location
Nucleus
Cell membrane
Colocalizes with PLXNB3 at the plasma membrane (PubMed:16122393).
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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