RPRD1A

P15RS is upregulated in cells overexpressing cyclin-dependent kinase inhibitor p15(INK4b) (CDKN2B; MIM 600431) and may have a role in cell cycle regulation (Liu et al., 2002 [PubMed 12470661]).[supplied by OMIM
Full Name
RPRD1A
Function
Interacts with phosphorylated C-terminal heptapeptide repeat domain (CTD) of the largest RNA polymerase II subunit POLR2A, and participates in dephosphorylation of the CTD by RPAP2. May act as a negative regulator of cyclin-D1 (CCND1) and cyclin-E (CCNE1) in the cell cycle.
Biological Process
Biological Process dephosphorylation of RNA polymerase II C-terminal domainManual Assertion Based On ExperimentIMP:UniProtKB
Biological Process mRNA 3'-end processingManual Assertion Based On ExperimentIBA:GO_Central
Cellular Location
Nucleus
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Anti-RPRD1A antibodies

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Target: RPRD1A
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: F-3
Application*: WB, IP, IF, E
Target: RPRD1A
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: C-6
Application*: WB, IP, IF, E
Target: RPRD1A
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: A-3
Application*: WB, IP, IF, E
Target: RPRD1A
Host: Mouse
Antibody Isotype: IgG2b, κ
Specificity: Human, Mouse, Rat
Clone: 1B8
Application*: E, IH, WB
Target: RPRD1A
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: 1D9
Application*: IP, M
Target: RPRD1A
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: 1B2
Application*: IP, M, WB
More Infomation
Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized) Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)
For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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