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RPRD1A

P15RS is upregulated in cells overexpressing cyclin-dependent kinase inhibitor p15(INK4b) (CDKN2B; MIM 600431) and may have a role in cell cycle regulation (Liu et al., 2002 [PubMed 12470661]).[supplied by OMIM

Full Name

RPRD1A

Function

Interacts with phosphorylated C-terminal heptapeptide repeat domain (CTD) of the largest RNA polymerase II subunit POLR2A, and participates in dephosphorylation of the CTD by RPAP2. May act as a negative regulator of cyclin-D1 (CCND1) and cyclin-E (CCNE1) in the cell cycle.

Biological Process

Biological Process dephosphorylation of RNA polymerase II C-terminal domainManual Assertion Based On ExperimentIMP:UniProtKB
Biological Process mRNA 3'-end processingManual Assertion Based On ExperimentIBA:GO_Central

Cellular Location

Nucleus

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Anti-RPRD1A antibodies

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Mouse Anti-RPRD1A Recombinant Antibody (F-3) (CBMAB-P3617-YC)

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Target: RPRD1A

Host: Mouse

Antibody Isotype: IgG

Specificity: Human

Clone: F-3

Application*: WB, IP, IF, E

Mouse Anti-RPRD1A Recombinant Antibody (C-6) (CBMAB-P3616-YC)

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Target: RPRD1A

Host: Mouse

Antibody Isotype: IgG

Specificity: Human

Clone: C-6

Application*: WB, IP, IF, E

Mouse Anti-RPRD1A Recombinant Antibody (A-3) (CBMAB-P3615-YC)

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Target: RPRD1A

Host: Mouse

Antibody Isotype: IgG

Specificity: Human

Clone: A-3

Application*: WB, IP, IF, E

Mouse Anti-RPRD1A Recombinant Antibody (1B8) (CBMAB-P3614-YC)

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Target: RPRD1A

Host: Mouse

Antibody Isotype: IgG2b, κ

Specificity: Human, Mouse, Rat

Clone: 1B8

Application*: E, IH, WB

Mouse Anti-RPRD1A Monoclonal Antibody (1D9) (CBMAB-0058-LY)

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Target: RPRD1A

Host: Mouse

Antibody Isotype: IgG2a

Specificity: Human

Clone: 1D9

Application*: IP, M

Mouse Anti-RPRD1A Monoclonal Antibody (1B2) (CBMAB-0057-LY)

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Target: RPRD1A

Host: Mouse

Antibody Isotype: IgG2a

Specificity: Human

Clone: 1B2

Application*: IP, M, WB

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Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized)

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(P): Predicted

* Abbreviations

AActivation
AGAgonist
APApoptosis
BBlocking
BABioassay
BIBioimaging
CImmunohistochemistry-Frozen Sections
CIChromatin Immunoprecipitation
CTCytotoxicity
CSCostimulation
DDepletion
DBDot Blot

EELISA
ECELISA(Cap)
EDELISA(Det)
ESELISpot
EMElectron Microscopy
FFlow Cytometry
FNFunction Assay
GSGel Supershift
IInhibition
IAEnzyme Immunoassay
ICImmunocytochemistry
IDImmunodiffusion
IEImmunoelectrophoresis

IFImmunofluorescence
IGImmunochromatography
IHImmunohistochemistry
IMImmunomicroscopy
IOImmunoassay
IPImmunoprecipitation
ISIntracellular Staining for Flow Cytometry
LALuminex Assay
LFLateral Flow Immunoassay
MMicroarray
MCMass Cytometry/CyTOF
MDMeDIP

MSElectrophoretic Mobility Shift Assay
NNeutralization
PImmunohistologyp-Paraffin Sections
PAPeptide Array
PEPeptide ELISA
PLProximity Ligation Assay
RRadioimmunoassay
SStimulation
SESandwich ELISA
SHIn situ hybridization
TCTissue Culture
WBWestern Blot

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