RTF2

RTF2 (Replication Termination Factor 2) is a Protein Coding gene.
Full Name
Replication Termination Factor 2
Function
Replication termination factor which is a component of the elongating replisome (Probable). Required for ATR pathway signaling upon DNA damage and has a positive activity during DNA replication. Might function to facilitate fork pausing at replication fork barriers like the rDNA. May be globally required to stimulate ATR signaling after the fork stalls or encounters a lesion (Probable). Interacts with nascent DNA (PubMed:29290612).
Biological Process
Biological Process cellular response to hydroxyureaManual Assertion Based On ExperimentIMP:UniProtKB
Biological Process mitotic DNA replication terminationIEA:InterPro
Biological Process regulation of DNA stabilityManual Assertion Based On ExperimentIMP:UniProtKB
Cellular Location
Chromosome
Localizes at the replication fork.
PTM
Undergoes proteasomal degradation, via DDI1 and DDI2. Removal from stalled replisomes and degradation are required for genome stability.
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Anti-RTF2 antibodies

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Mouse Anti-RTF2 Recombinant Antibody (CBWJC-4382) (CBMAB-C5763WJ)

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Target: RTF2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Monkey
Clone: CBWJC-4382
Application*: WB, IF, F
Datasheet SDS

Mouse Anti-RTF2 Recombinant Antibody (CBWJC-4381) (CBMAB-C5762WJ)

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Target: RTF2
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: CBWJC-4381
Application*: WB, IH, IF, F
Datasheet SDS

Mouse Anti-RTF2 Recombinant Antibody (CBYY-C3250) (CBMAB-C4693-YY)

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Target: RTF2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYY-C3250
Application*: WB, IF
Datasheet SDS

Mouse Anti-RTF2 Recombinant Antibody (CBFYC-3083) (CBMAB-C3160-FY)

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Target: RTF2
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: CBFYC-3083
Application*: WB, F, IH, IF, P
Datasheet SDS

Mouse Anti-RTF2 Recombinant Antibody (7 E10) (CBMAB-C8391-LY)

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Target: RTF2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 7 E10
Application*: IF, WB
Datasheet SDS

Mouse Anti-RTF2 Recombinant Antibody (3A5) (CBMAB-C5654-LY)

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Target: RTF2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 3A5
Application*: F, IF, WB
Datasheet SDS

Mouse Anti-RTF2 Recombinant Antibody (1E8) (CBMAB-C3988-LY)

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Target: RTF2
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: 1E8
Application*: WB, F, IH, IC/IF, P
Datasheet SDS

Mouse Anti-RTF2 Recombinant Antibody (7H1) (CBMAB-R3783-CN)

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Target: RTF2
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: 7H1
Application*: F, IF, WB
Datasheet SDS

Mouse Anti-RTF2 Recombinant Antibody (7E10) (CBMAB-R3782-CN)

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Target: RTF2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 7E10
Application*: IF, WB
Datasheet SDS
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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IGImmunochromatography
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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