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RXFP4

GPR100 is a member of the rhodopsin family of G protein-coupled receptors (GPRs).

Full Name

relaxin family peptide/INSL5 receptor 4

Function

High affinity receptor for INSL5. Also acts as receptor for RLN3/relaxin-3, as well as bradykinin and kallidin. Binding of the ligand inhibit cAMP accumulation.

Biological Process

Biological Process neuropeptide signaling pathwayManual Assertion Based On ExperimentIBA:GO_Central
Biological Process positive regulation of feeding behaviorIEA:Ensembl

Cellular Location

Cell membrane

Topology

Extracellular: 1-43
Helical: 44-64
Cytoplasmic: 65-78
Helical: 79-99
Extracellular: 100-116
Helical: 117-137
Cytoplasmic: 138-154
Helical: 155-175
Extracellular: 176-209
Helical: 210-230
Cytoplasmic: 231-249
Helical: 250-270
Extracellular: 271-281
Helical: 282-302
Cytoplasmic: 303-374

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Anti-RXFP4 antibodies

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Rabbit Anti-RXFP4 Recombinant Antibody (EG1354) (CBMAB-EN1633-LY)

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Target: RXFP4

Host: Rabbit

Antibody Isotype: IgG

Specificity: Human

Clone: EG1354

Application*: WB: 1:500~1:1000 IF: 1:100~1:500 ELISA: 1:5000

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Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized)

Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)

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Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized)

Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)

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For Research Use Only. Not For Clinical Use.

(P): Predicted

* Abbreviations

AActivation
AGAgonist
APApoptosis
BBlocking
BABioassay
BIBioimaging
CImmunohistochemistry-Frozen Sections
CIChromatin Immunoprecipitation
CTCytotoxicity
CSCostimulation
DDepletion
DBDot Blot

EELISA
ECELISA(Cap)
EDELISA(Det)
ESELISpot
EMElectron Microscopy
FFlow Cytometry
FNFunction Assay
GSGel Supershift
IInhibition
IAEnzyme Immunoassay
ICImmunocytochemistry
IDImmunodiffusion
IEImmunoelectrophoresis

IFImmunofluorescence
IGImmunochromatography
IHImmunohistochemistry
IMImmunomicroscopy
IOImmunoassay
IPImmunoprecipitation
ISIntracellular Staining for Flow Cytometry
LALuminex Assay
LFLateral Flow Immunoassay
MMicroarray
MCMass Cytometry/CyTOF
MDMeDIP

MSElectrophoretic Mobility Shift Assay
NNeutralization
PImmunohistologyp-Paraffin Sections
PAPeptide Array
PEPeptide ELISA
PLProximity Ligation Assay
RRadioimmunoassay
SStimulation
SESandwich ELISA
SHIn situ hybridization
TCTissue Culture
WBWestern Blot

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