RXFP4

GPR100 is a member of the rhodopsin family of G protein-coupled receptors (GPRs).

Full Name

relaxin family peptide/INSL5 receptor 4

Function

High affinity receptor for INSL5. Also acts as receptor for RLN3/relaxin-3, as well as bradykinin and kallidin. Binding of the ligand inhibit cAMP accumulation.

Biological Process

Biological Process neuropeptide signaling pathwayManual Assertion Based On ExperimentIBA:GO_Central
Biological Process positive regulation of feeding behaviorIEA:Ensembl

Cellular Location

Cell membrane

Topology

Extracellular: 1-43
Helical: 44-64
Cytoplasmic: 65-78
Helical: 79-99
Extracellular: 100-116
Helical: 117-137
Cytoplasmic: 138-154
Helical: 155-175
Extracellular: 176-209
Helical: 210-230
Cytoplasmic: 231-249
Helical: 250-270
Extracellular: 271-281
Helical: 282-302
Cytoplasmic: 303-374

Anti-RXFP4 antibodies

Rabbit Anti-RXFP4 Recombinant Antibody (EG1354) (CBMAB-EN1633-LY)

Datasheet

SDS

Target: RXFP4

Host: Rabbit

Antibody Isotype: IgG

Specificity: Human

Clone: EG1354

Application*: WB: 1:500~1:1000 IF: 1:100~1:500 ELISA: 1:5000

For Research Use Only. Not For Clinical Use.

(P): Predicted

* Abbreviations

IFImmunofluorescence

IHImmunohistochemistry

IPImmunoprecipitation

WBWestern Blot

EELISA

MMicroarray

CIChromatin Immunoprecipitation

FFlow Cytometry

FNFunction Assay

IDImmunodiffusion

RRadioimmunoassay

TCTissue Culture

GSGel Supershift

NNeutralization

BBlocking

AActivation

IInhibition

DDepletion

ESELISpot

DBDot Blot

MCMass Cytometry/CyTOF

CTCytotoxicity

SStimulation

AGAgonist

APApoptosis

IMImmunomicroscopy

BABioassay

CSCostimulation

EMElectron Microscopy

IEImmunoelectrophoresis

PAPeptide Array

ICImmunocytochemistry

PEPeptide ELISA

MDMeDIP

SHIn situ hybridization

IAEnzyme Immunoassay

SEsandwich ELISA

PLProximity Ligation Assay

ECELISA(Cap)

EDELISA(Det)

BIBioimaging

IOImmunoassay

LFLateral Flow Immunoassay

LALuminex Assay

CImmunohistochemistry-Frozen Sections

PImmunohistologyp-Paraffin Sections

ISIntracellular Staining for Flow Cytometry

MSElectrophoretic Mobility Shift Assay

RIRNA Binding Protein Immunoprecipitation (RIP)