RXFP4
GPR100 is a member of the rhodopsin family of G protein-coupled receptors (GPRs).
Full Name
relaxin family peptide/INSL5 receptor 4
Function
High affinity receptor for INSL5. Also acts as receptor for RLN3/relaxin-3, as well as bradykinin and kallidin. Binding of the ligand inhibit cAMP accumulation.
Biological Process
Biological Process neuropeptide signaling pathwayManual Assertion Based On ExperimentIBA:GO_Central
Biological Process positive regulation of feeding behaviorIEA:Ensembl
Biological Process positive regulation of feeding behaviorIEA:Ensembl
Cellular Location
Cell membrane
Topology
Extracellular: 1-43
Helical: 44-64
Cytoplasmic: 65-78
Helical: 79-99
Extracellular: 100-116
Helical: 117-137
Cytoplasmic: 138-154
Helical: 155-175
Extracellular: 176-209
Helical: 210-230
Cytoplasmic: 231-249
Helical: 250-270
Extracellular: 271-281
Helical: 282-302
Cytoplasmic: 303-374
Helical: 44-64
Cytoplasmic: 65-78
Helical: 79-99
Extracellular: 100-116
Helical: 117-137
Cytoplasmic: 138-154
Helical: 155-175
Extracellular: 176-209
Helical: 210-230
Cytoplasmic: 231-249
Helical: 250-270
Extracellular: 271-281
Helical: 282-302
Cytoplasmic: 303-374
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Anti-RXFP4 antibodies
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Target: RXFP4
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: EG1354
Application*: WB: 1:500~1:1000 IF: 1:100~1:500 ELISA: 1:5000
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For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
- AActivation
- AGAgonist
- APApoptosis
- BBlocking
- BABioassay
- BIBioimaging
- CImmunohistochemistry-Frozen Sections
- CIChromatin Immunoprecipitation
- CTCytotoxicity
- CSCostimulation
- DDepletion
- DBDot Blot
- EELISA
- ECELISA(Cap)
- EDELISA(Det)
- ESELISpot
- EMElectron Microscopy
- FFlow Cytometry
- FNFunction Assay
- GSGel Supershift
- IInhibition
- IAEnzyme Immunoassay
- ICImmunocytochemistry
- IDImmunodiffusion
- IEImmunoelectrophoresis
- IFImmunofluorescence
- IHImmunohistochemistry
- IMImmunomicroscopy
- IOImmunoassay
- IPImmunoprecipitation
- ISIntracellular Staining for Flow Cytometry
- LALuminex Assay
- LFLateral Flow Immunoassay
- MMicroarray
- MCMass Cytometry/CyTOF
- MDMeDIP
- MSElectrophoretic Mobility Shift Assay
- NNeutralization
- PImmunohistologyp-Paraffin Sections
- PAPeptide Array
- PEPeptide ELISA
- PLProximity Ligation Assay
- RRadioimmunoassay
- SStimulation
- SESandwich ELISA
- SHIn situ hybridization
- TCTissue Culture
- WBWestern Blot

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