S100A11
The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in motility, invasion, and tubulin polymerization. Chromosomal rearrangements and altered expression of this gene have been implicated in tumor metastasis. [provided by RefSeq, Jul 2008]
Full Name
S100 Calcium Binding Protein A11
Function
Facilitates the differentiation and the cornification of keratinocytes.
Biological Process
Biological Process negative regulation of cell population proliferationManual Assertion Based On ExperimentTAS:ProtInc
Biological Process negative regulation of DNA replicationManual Assertion Based On ExperimentTAS:ProtInc
Biological Process positive regulation of smooth muscle cell migrationManual Assertion Based On ExperimentIMP:CACAO
Biological Process signal transductionManual Assertion Based On ExperimentTAS:UniProtKB
Biological Process negative regulation of DNA replicationManual Assertion Based On ExperimentTAS:ProtInc
Biological Process positive regulation of smooth muscle cell migrationManual Assertion Based On ExperimentIMP:CACAO
Biological Process signal transductionManual Assertion Based On ExperimentTAS:UniProtKB
Cellular Location
Cytoplasm
Nucleus
Nucleus
PTM
Phosphorylation at Thr-10 by PRKCA significantly suppresses homodimerization and promotes association with NCL/nucleolin which induces nuclear translocation.
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Anti-S100A11 antibodies
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CompareTarget: S100A11
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Mouse
Clone: CF380
Application*: ELISA, WB, IHC
Target: S100A11
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: 1B12
Application*: WB, E
Target: S100A11
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: TS106
Application*: WB
Target: S100A11
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: CBXS-2917
Application*: E, IF, IH, WB
Target: S100A11
Host: Mouse
Specificity: Human
Clone: CBXS-2687
Application*: E, WB
Target: S100A11
Host: Rat
Specificity: Mouse
Clone: CBXS-2617
Application*: WB
Target: S100A11
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: CBXS-1881
Application*: WB
Target: S100A11
Host: Rat
Antibody Isotype: IgG2a
Specificity: Mouse
Clone: CBXS-1838
Application*: WB
Target: S100A11
Host: Rabbit
Antibody Isotype: IgG
Specificity: Mouse, Rat, Human
Clone: CBXS-1275
Application*: WB, P, F, IF
Target: S100A11
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: CBXS-1274
Application*: WB, F, IF
Target: S100A11
Host: Mouse
Specificity: Rat
Clone: CBXS-0073
Application*: WB, IC, P, C, E
Target: S100A11
Host: Mouse
Specificity: Human
Clone: CBXS-0072
Application*: WB, IC, P, C, E
Target: S100A11
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBXS-5579
Application*: E, WB
Target: S100A11
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CBXS-4258
Application*: WB, F, E, IF
Target: S100A11
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Mouse
Clone: CBXS-3809
Application*: E, WB, IH, IR
Target: S100A11
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: CBXS-3644
Application*: E
Target: S100A11
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: 2F4
Application*: E, IF, WB
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(P): Predicted
* Abbreviations
- AActivation
- AGAgonist
- APApoptosis
- BBlocking
- BABioassay
- BIBioimaging
- CImmunohistochemistry-Frozen Sections
- CIChromatin Immunoprecipitation
- CTCytotoxicity
- CSCostimulation
- DDepletion
- DBDot Blot
- EELISA
- ECELISA(Cap)
- EDELISA(Det)
- ESELISpot
- EMElectron Microscopy
- FFlow Cytometry
- FNFunction Assay
- GSGel Supershift
- IInhibition
- IAEnzyme Immunoassay
- ICImmunocytochemistry
- IDImmunodiffusion
- IEImmunoelectrophoresis
- IFImmunofluorescence
- IGImmunochromatography
- IHImmunohistochemistry
- IMImmunomicroscopy
- IOImmunoassay
- IPImmunoprecipitation
- ISIntracellular Staining for Flow Cytometry
- LALuminex Assay
- LFLateral Flow Immunoassay
- MMicroarray
- MCMass Cytometry/CyTOF
- MDMeDIP
- MSElectrophoretic Mobility Shift Assay
- NNeutralization
- PImmunohistologyp-Paraffin Sections
- PAPeptide Array
- PEPeptide ELISA
- PLProximity Ligation Assay
- RRadioimmunoassay
- SStimulation
- SESandwich ELISA
- SHIn situ hybridization
- TCTissue Culture
- WBWestern Blot
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