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Rat Anti-S100A11 Recombinant Antibody (CBXS-2617) (CBMAB-S5371-CQ)

This product is a rat antibody that recognizes S100A11. The antibody CBXS-2617 can be used for immunoassay techniques such as: WB.
See all S100A11 antibodies

Summary

Host Animal
Rat
Specificity
Mouse
Clone
CBXS-2617
Application
WB

Basic Information

Immunogen
Recombinant protein corresponding to mouse S100A11
Specificity
Mouse
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Lyophilized
Concentration
LYOPH
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
S100 Calcium Binding Protein A11
Introduction
The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in motility, invasion, and tubulin polymerization. Chromosomal rearrangements and altered expression of this gene have been implicated in tumor metastasis.
Entrez Gene ID
UniProt ID
Alternative Names
EMAPI; Emap1; S100a14; S100c; cal
Function
Facilitates the differentiation and the cornification of keratinocytes.
Biological Process
Biological Process negative regulation of cell population proliferationManual Assertion Based On ExperimentTAS:ProtInc
Biological Process negative regulation of DNA replicationManual Assertion Based On ExperimentTAS:ProtInc
Biological Process positive regulation of smooth muscle cell migrationManual Assertion Based On ExperimentIMP:CACAO
Biological Process signal transductionManual Assertion Based On ExperimentTAS:UniProtKB
Cellular Location
Cytoplasm
Nucleus
PTM
Phosphorylation at Thr-10 by PRKCA significantly suppresses homodimerization and promotes association with NCL/nucleolin which induces nuclear translocation.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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