SDF4

This gene encodes a stromal cell derived factor that is a member of the CREC protein family. The encoded protein contains six EF-hand motifs and calcium-binding motifs. This protein localizes to the Golgi lumen and may be involved in regulating calcium dependent cellular activities.

Full Name

Stromal Cell Derived Factor 4

Function

May regulate calcium-dependent activities in the endoplasmic reticulum lumen or post-ER compartment.
Isoform 5 may be involved in the exocytosis of zymogens by pancreatic acini.

Biological Process

Biological Process calcium-ion regulated exocytosisBy SimilarityISS:BHF-UCL
Biological Process cerebellum developmentBy SimilarityISS:BHF-UCL
Biological Process fat cell differentiationISS:BHF-UCL
Biological Process maintenance of synapse structureManual Assertion Based On ExperimentIGI:FlyBase
Biological Process response to ethanolBy SimilarityISS:BHF-UCL
Biological Process UV protectionBy SimilarityISS:BHF-UCL
Biological Process zymogen granule exocytosisBy SimilarityISS:BHF-UCL

Cellular Location

Isoform 1
Golgi apparatus lumen
Isoform 5
Cytoplasm
Cell membrane
Cell projection, bleb
Isoform 5 colocalizes with STX3 and STXBP1 isoform 2 at the plasma membrane and cell surface blebs.