SEMA6C

This gene encodes a member of the semaphorin family. Semaphorins represent important molecular signals controlling multiple aspects of the cellular response that follows CNS injury, and thus may play an important role in neural regeneration.
Full Name
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6C
Function
Shows growth cone collapsing activity on dorsal root ganglion (DRG) neurons in vitro. May be a stop signal for the DRG neurons in their target areas, and possibly also for other neurons. May also be involved in the maintenance and remodeling of neuronal connections.
Biological Process
Biological Process axon guidanceManual Assertion Based On ExperimentIBA:GO_Central
Biological Process negative chemotaxisManual Assertion Based On ExperimentIBA:GO_Central
Biological Process negative regulation of axon extensionIDA:UniProtKB
Biological Process negative regulation of axon extension involved in axon guidanceManual Assertion Based On ExperimentIBA:GO_Central
Biological Process neural crest cell migrationManual Assertion Based On ExperimentIBA:GO_Central
Biological Process positive regulation of cell migrationManual Assertion Based On ExperimentIBA:GO_Central
Biological Process semaphorin-plexin signaling pathwayManual Assertion Based On ExperimentIBA:GO_Central
Cellular Location
Cell membrane
Topology
Extracellular: 25-604
Helical: 605-625
Cytoplasmic: 626-930
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Anti-SEMA6C antibodies

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Rat Anti-SEMA6C Recombinant Antibody (CBXS-5708) (CBMAB-S0576-CQ)

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Target: SEMA6C
Host: Rat
Antibody Isotype: IgG2
Specificity: Mouse
Clone: CBXS-5708
Application*: IH, WB
Datasheet SDS

Rat Anti-SEMA6C Recombinant Antibody (CBXS-2558) (CBMAB-S5314-CQ)

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Target: SEMA6C
Host: Rat
Antibody Isotype: IgG2
Specificity: Mouse
Clone: CBXS-2558
Application*: IH, WB
Datasheet SDS

Mouse Anti-SEMA6C Recombinant Antibody (CBXS-2557) (CBMAB-S5313-CQ)

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Target: SEMA6C
Host: Mouse
Antibody Isotype: IgG2
Specificity: Human
Clone: CBXS-2557
Application*: WB
Datasheet SDS

Rat Anti-SEMA6C Recombinant Antibody (CBXS-1740) (CBMAB-S4566-CQ)

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Target: SEMA6C
Host: Rat
Antibody Isotype: IgG2a
Specificity: Mouse
Clone: CBXS-1740
Application*: WB, IH
Datasheet SDS

Mouse Anti-SEMA6C Recombinant Antibody (CBXS-1736) (CBMAB-S4562-CQ)

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Target: SEMA6C
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: CBXS-1736
Application*: WB
Datasheet SDS
More Infomation
Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized) Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)

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For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IGImmunochromatography
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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