SEPT11

SEPT11 belongs to the conserved septin family of filament-forming cytoskeletal GTPases that are involved in a variety of cellular functions including cytokinesis and vesicle trafficking (Hanai et al., 2004 [PubMed 15196925]; Nagata et al., 2004 [PubMed 15485874]).[supplied by OMIM
Full Name
septin 11
Function
Filament-forming cytoskeletal GTPase. May play a role in cytokinesis (Potential). May play a role in the cytoarchitecture of neurons, including dendritic arborization and dendritic spines, and in GABAergic synaptic connectivity (By similarity).
During Listeria monocytogenes infection, not required for the bacterial entry process, but restricts its efficacy.
Biological Process
Biological Process cytoskeleton-dependent cytokinesisManual Assertion Based On ExperimentIBA:GO_Central
Biological Process protein localizationManual Assertion Based On ExperimentIBA:GO_Central
Cellular Location
Cytoplasm, cytoskeleton
Synapse
Cell projection, dendritic spine
Cell projection, axon
Partly colocalizes with stress fibers and microtubules. During bacterial infection, displays a collar shape structure next to actin at the pole of invading bacteria.
Involvement in disease
A chromosomal aberration involving SEPTIN11 may be a cause of chronic neutrophilic leukemia. Translocation t(4;11)(q21;q23) with KMT2A/MLL1.
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Anti-SEPT11 antibodies

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Mouse Anti-SEPT11 Recombinant Antibody (1E5) (CBMAB-C4270-CN)

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Target: SEPT11
Host: Mouse
Antibody Isotype: IgG2b, λ
Specificity: Human
Clone: 1E5
Application*: E, WB
Datasheet SDS

Mouse Anti-SEPT11 Recombinant Antibody (CBXS-2763) (CBMAB-S5514-CQ)

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Target: SEPT11
Host: Mouse
Antibody Isotype: IgG2b, λ
Specificity: Human
Clone: CBXS-2763
Application*: E, WB
Datasheet SDS

Mouse Anti-SEPT11 (N-Term) Recombinant Antibody (CBXS-0213) (CBMAB-S3196-CQ)

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Target: SEPT11
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBXS-0213
Application*: WB
Datasheet SDS

Mouse Anti-SEPT11 Recombinant Antibody (CBXS-5954) (CBMAB-S0801-CQ)

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Target: SEPT11
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBXS-5954
Application*: DB, IC, WB
Datasheet SDS

Mouse Anti-SEPT11 Recombinant Antibody (998C6a) (CBMAB-0818CQ)

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Target: SEPT11
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 998C6a
Application*: WB, DB
Datasheet SDS
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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IGImmunochromatography
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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