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SFMBT1

This gene shares high similarity with the Drosophila Scm (sex comb on midleg) gene. It encodes a protein which contains four malignant brain tumor repeat (mbt) domains and may be involved in antigen recognition. [provided by RefSeq, Jun 2012]
Full Name
Scm Like With Four Mbt Domains 1
Function
Histone-binding protein, which is part of various corepressor complexes. Mediates the recruitment of corepressor complexes to target genes, followed by chromatin compaction and repression of transcription. Plays a role during myogenesis: required for the maintenance of undifferentiated states of myogenic progenitor cells via interaction with MYOD1. Interaction with MYOD1 leads to the recruitment of associated corepressors and silencing of MYOD1 target genes. Part of the SLC complex in germ cells, where it may play a role during spermatogenesis.
Biological Process
Biological Process cell differentiationIEA:UniProtKB-KW
Biological Process chromatin organizationIEA:UniProtKB-KW
Biological Process negative regulation of DNA-templated transcriptionManual Assertion Based On ExperimentIDA:UniProtKB
Biological Process negative regulation of muscle organ developmentManual Assertion Based On ExperimentIMP:UniProtKB
Biological Process spermatogenesisIEA:UniProtKB-KW
Cellular Location
Nucleus
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Anti-SFMBT1 antibodies

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Mouse Anti-SFMBT1 Monoclonal Antibody (2C1) (CBMAB-0093-LY)

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Target: SFMBT1
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: 2C1
Application*: IP, M
Datasheet SDS

SFMBT1 Matched Antibody Pair (1075) (APMAB-1075LY)

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Target: SFMBT1
Specificity: Human
Datasheet SDS

Mouse Anti-SFMBT1 Recombinant Antibody (2A1) (CBMAB-A8025-LY)

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Target: SFMBT1
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: 2A1
Application*: WB, E
Datasheet SDS

Mouse Anti-SFMBT1 Recombinant Antibody (CBXS-0294) (CBMAB-S3269-CQ)

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Target: SFMBT1
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: CBXS-0294
Application*: IP
Datasheet SDS

Mouse Anti-SFMBT1 Recombinant Antibody (CBXS-4321) (CBMAB-S1566-CQ)

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Target: SFMBT1
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: CBXS-4321
Application*: WB, E
Datasheet SDS
More Infomation
Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized) Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)

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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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