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SH2D4A

SH2 domain-containing protein 4A is a protein that in humans is encoded by the SH2D4A gene. This protein inhibits estrogen-induced cell proliferation by competing with PLCG for binding to ESR1, blocking the effect of estrogen on PLCG and repressing estrogen-induced proliferation. It may play a role in T-cell development and function.

Full Name

SH2D4A

Function

Inhibits estrogen-induced cell proliferation by competing with PLCG for binding to ESR1, blocking the effect of estrogen on PLCG and repressing estrogen-induced proliferation. May play a role in T-cell development and function.

Cellular Location

Cytoplasm
Located at podocyte foot processes.

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Anti-SH2D4A antibodies

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Mouse Anti-SH2D4A Recombinant Antibody (3G8) (CBMAB-A8084-LY)

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Target: SH2D4A

Host: Mouse

Antibody Isotype: IgG2a, κ

Specificity: Human

Clone: 3G8

Application*: WB, E

Mouse Anti-SH2D4A Recombinant Antibody (CBXS-2217) (CBMAB-S4979-CQ)

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Target: SH2D4A

Host: Mouse

Specificity: Human

Clone: CBXS-2217

Application*: WB, IP, IF, E

Mouse Anti-SH2D4A Recombinant Antibody (CBXS-4931) (CBMAB-S2153-CQ)

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Target: SH2D4A

Host: Mouse

Antibody Isotype: IgG2a, κ

Specificity: Human

Clone: CBXS-4931

Application*: E, IF, P, WB

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Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized)

Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)

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For Research Use Only. Not For Clinical Use.

(P): Predicted

* Abbreviations

AActivation
AGAgonist
APApoptosis
BBlocking
BABioassay
BIBioimaging
CImmunohistochemistry-Frozen Sections
CIChromatin Immunoprecipitation
CTCytotoxicity
CSCostimulation
DDepletion
DBDot Blot

EELISA
ECELISA(Cap)
EDELISA(Det)
ESELISpot
EMElectron Microscopy
FFlow Cytometry
FNFunction Assay
GSGel Supershift
IInhibition
IAEnzyme Immunoassay
ICImmunocytochemistry
IDImmunodiffusion
IEImmunoelectrophoresis

IFImmunofluorescence
IGImmunochromatography
IHImmunohistochemistry
IMImmunomicroscopy
IOImmunoassay
IPImmunoprecipitation
ISIntracellular Staining for Flow Cytometry
LALuminex Assay
LFLateral Flow Immunoassay
MMicroarray
MCMass Cytometry/CyTOF
MDMeDIP

MSElectrophoretic Mobility Shift Assay
NNeutralization
PImmunohistologyp-Paraffin Sections
PAPeptide Array
PEPeptide ELISA
PLProximity Ligation Assay
RRadioimmunoassay
SStimulation
SESandwich ELISA
SHIn situ hybridization
TCTissue Culture
WBWestern Blot

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