SH2D4A

SH2 domain-containing protein 4A is a protein that in humans is encoded by the SH2D4A gene. This protein inhibits estrogen-induced cell proliferation by competing with PLCG for binding to ESR1, blocking the effect of estrogen on PLCG and repressing estrogen-induced proliferation. It may play a role in T-cell development and function.

Full Name

SH2D4A

Function

Inhibits estrogen-induced cell proliferation by competing with PLCG for binding to ESR1, blocking the effect of estrogen on PLCG and repressing estrogen-induced proliferation. May play a role in T-cell development and function.

Cellular Location

Cytoplasm
Located at podocyte foot processes.

Anti-SH2D4A antibodies

Mouse Anti-SH2D4A Recombinant Antibody (3G8) (CBMAB-A8084-LY)

Datasheet

SDS

Target: SH2D4A

Host: Mouse

Antibody Isotype: IgG2a, κ

Specificity: Human

Clone: 3G8

Application*: WB, E

Mouse Anti-SH2D4A Recombinant Antibody (CBXS-4931) (CBMAB-S2153-CQ)

Datasheet

SDS

Target: SH2D4A

Host: Mouse

Antibody Isotype: IgG2a, κ

Specificity: Human

Clone: CBXS-4931

Application*: E, IF, P, WB

Mouse Anti-SH2D4A Recombinant Antibody (CBXS-2217) (CBMAB-S4979-CQ)

Datasheet

SDS

Target: SH2D4A

Host: Mouse

Specificity: Human

Clone: CBXS-2217

Application*: WB, IP, IF, E

For Research Use Only. Not For Clinical Use.

(P): Predicted

* Abbreviations

IFImmunofluorescence

IHImmunohistochemistry

IPImmunoprecipitation

WBWestern Blot

EELISA

MMicroarray

CIChromatin Immunoprecipitation

FFlow Cytometry

FNFunction Assay

IDImmunodiffusion

RRadioimmunoassay

TCTissue Culture

GSGel Supershift

NNeutralization

BBlocking

AActivation

IInhibition

DDepletion

ESELISpot

DBDot Blot

MCMass Cytometry/CyTOF

CTCytotoxicity

SStimulation

AGAgonist

APApoptosis

IMImmunomicroscopy

BABioassay

CSCostimulation

EMElectron Microscopy

IEImmunoelectrophoresis

PAPeptide Array

ICImmunocytochemistry

PEPeptide ELISA

MDMeDIP

SHIn situ hybridization

IAEnzyme Immunoassay

SEsandwich ELISA

PLProximity Ligation Assay

ECELISA(Cap)

EDELISA(Det)

BIBioimaging

IOImmunoassay

LFLateral Flow Immunoassay

LALuminex Assay

CImmunohistochemistry-Frozen Sections

PImmunohistologyp-Paraffin Sections

ISIntracellular Staining for Flow Cytometry

MSElectrophoretic Mobility Shift Assay

RIRNA Binding Protein Immunoprecipitation (RIP)