SIGLEC6

This gene encodes a member of the SIGLEC (sialic acid binding immunoglobulin-like lectin) family of proteins. The encoded transmembrane receptor binds sialyl-TN glycans and leptin. Placental expression of the encoded protein is upregulated in preeclampsia. [provided by RefSeq, Jul 2016]
Full Name
Sialic Acid Binding Ig Like Lectin 6
Function
Putative adhesion molecule that mediates sialic-acid dependent binding to cells. Binds to alpha-2,6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface.
Biological Process
Biological Process cell adhesionManual Assertion Based On ExperimentIBA:GO_Central
Biological Process cell-cell signalingManual Assertion Based On ExperimentTAS:ProtInc
Cellular Location
Isoform 1
Cell membrane
Isoform 2
Secreted
Topology
Extracellular: 27-347
Helical: 348-368
Cytoplasmic: 369-453
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Anti-SIGLEC6 antibodies

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Mouse Anti-SIGLEC6 Recombinant Antibody (2G6) (CBMAB-A8124-LY)

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Target: SIGLEC6
Host: Mouse
Antibody Isotype: IgG2b, κ
Specificity: Human
Clone: 2G6
Application*: WB, E
Datasheet SDS

Human Recombinant SIGLEC6 protein, His Tag-1 (V2LY-0526-LY6804)

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Target: SIGLEC6
Expressed Host: HEK293 Cells
Sequence: Amino Acid: 27-331
Tag: His Tag
Datasheet SDS

Human Recombinant SIGLEC6 protein, His Tag (V2LY-0526-LY6803)

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Target: SIGLEC6
Expressed Host: HEK293 Cells
Sequence: Amino Acid: 27-331
Tag: His Tag
In Vivo Assay
Datasheet SDS

Human Recombinant SIGLEC6 protein, Biotin Conjugated, His & AVI Tag (V2LY-0526-LY6802)

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Target: SIGLEC6
Expressed Host: HEK293 Cells
Sequence: Amino Acid: 27-331
Tag: His & AVI Tag
Datasheet SDS

Human Recombinant SIGLEC6 protein, hFc Tag-1 (V2LY-0526-LY6801)

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Target: SIGLEC6
Expressed Host: HEK293 Cells
Sequence: Amino Acid: 27-331
Tag: hFc Tag
Datasheet SDS

Human Recombinant SIGLEC6 protein, hFc Tag (V2LY-0526-LY6800)

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Target: SIGLEC6
Expressed Host: HEK293 Cells
Sequence: Amino Acid: 27-331
Tag: hFc Tag
In Vivo Assay
Datasheet SDS

Cynomolgus Recombinant SIGLEC6 protein, ECD, His Tag-1 (V2LY-0526-LY1639)

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Target: SIGLEC6
Expressed Host: HEK293 Cells
Sequence: Amino Acid: 1-333
Tag: His Tag
In Vivo Assay
Datasheet SDS

Cynomolgus Recombinant SIGLEC6 protein, ECD, His Tag (V2LY-0526-LY1638)

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Target: SIGLEC6
Expressed Host: HEK293 Cells
Sequence: Amino Acid: 1-333
Tag: His Tag
Datasheet SDS

Mouse Anti-SIGLEC6 Recombinant Antibody (CBT2679) (V2LY-0625-LY1173)

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Target: SIGLEC6
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: CBT2679
Application*: IH, F
Datasheet SDS

SIGLEC6 Matched Antibody Pair (1095) (APMAB-1095LY)

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Target: SIGLEC6
Specificity: Human
Datasheet SDS

Mouse Anti-SIGLEC6 Recombinant Antibody (CBXS-2950) (CBMAB-S5699-CQ)

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Target: SIGLEC6
Host: Mouse
Antibody Isotype: IgG2b, κ
Specificity: Human
Clone: CBXS-2950
Application*: E, IP, WB
Datasheet SDS

Mouse Anti-SIGLEC6 Recombinant Antibody (CBXS-1933) (CBMAB-S0141-CQ)

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Target: SIGLEC6
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: CBXS-1933
Application*: F
Datasheet SDS

Human Anti-SIGLEC6 Recombinant Antibody (CBXC-0931) (CBMAB-C2047-CQ)

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Target: SIGLEC6
Host: Human
Antibody Isotype: IgG1
Specificity: Human
Clone: CBXC-0931
Application*: F
Datasheet SDS
More Infomation
Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized) Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)

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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IGImmunochromatography
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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