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Human Anti-SIGLEC6 Recombinant Antibody (CBXC-0931) (CBMAB-C2047-CQ)


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Summary

Host Animal
Human
Specificity
Human
Clone
CBXC-0931
Antibody Isotype
IgG1
Application
FC

Basic Information

Specificity
Human
Antibody Isotype
IgG1
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
Buffer containing stabilizer
Preservative
0.05% sodium azide
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
Sialic Acid Binding Ig Like Lectin 6
Introduction
This gene encodes a member of the SIGLEC (sialic acid binding immunoglobulin-like lectin) family of proteins. The encoded transmembrane receptor binds sialyl-TN glycans and leptin. Placental expression of the encoded protein is upregulated in preeclampsia.
Entrez Gene ID
946
UniProt ID
O43699
Alternative Names
Sialic Acid Binding Ig Like Lectin 6; Obesity-Binding Protein 1; CD33 Antigen-Like 1; CDW327; CD33L1; CD33L; OBBP1; Sialic Acid Binding Ig-Like Lectin 6;
Function
Putative adhesion molecule that mediates sialic-acid dependent binding to cells. Binds to alpha-2,6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface.
Biological Process
Biological Process cell adhesionManual Assertion Based On ExperimentIBA:GO_Central
Biological Process cell-cell signalingManual Assertion Based On ExperimentTAS:ProtInc
Cellular Location
Isoform 1
Cell membrane
Isoform 2
Secreted
Topology
Extracellular: 27-347
Helical: 348-368
Cytoplasmic: 369-453
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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