SLAMF8

This gene encodes a member of the CD2 family of cell surface proteins involved in lymphocyte activation. These proteins are characterized by Ig domains. This protein is expressed in lymphoid tissues, and studies of a similar protein in mouse suggest that it may function during B cell lineage commitment. The gene is found in a region of chromosome 1 containing many CD2 genes.
Full Name
SLAM Family Member 8
Function
May play a role in B-lineage commitment and/or modulation of signaling through the B-cell receptor.
Biological Process
Biological Process B-1 B cell lineage commitmentBy SimilarityISS:UniProtKB
Biological Process defense response to bacteriumISS:UniProtKB
Biological Process leukocyte chemotaxis involved in inflammatory responseISS:UniProtKB
Biological Process negative regulation of dendritic cell chemotaxisISS:UniProtKB
Biological Process negative regulation of macrophage chemotaxisISS:UniProtKB
Biological Process negative regulation of monocyte chemotaxisISS:UniProtKB
Biological Process negative regulation of neutrophil migrationISS:UniProtKB
Biological Process negative regulation of respiratory burst involved in inflammatory responseISS:UniProtKB
Biological Process phagosome acidificationISS:UniProtKB
Biological Process regulation of B cell differentiationBy SimilarityISS:UniProtKB
Biological Process regulation of kinase activityISS:UniProtKB
Biological Process regulation of NAD(P)H oxidase activityISS:UniProtKB
Cellular Location
Membrane
Topology
Extracellular: 23-233
Helical: 234-254
Cytoplasmic: 255-285
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Anti-SLAMF8 antibodies

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Mouse Anti-SLAMF8 Recombinant Antibody (CBXS-4293) (CBMAB-S1539-CQ)

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Target: SLAMF8
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBXS-4293
Application*: F
Datasheet SDS

Mouse Anti-SLAMF8 Recombinant Antibody (CBT2451) (V2LY-0625-LY1075)

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Target: SLAMF8
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: CBT2451
Application*: F
Datasheet SDS

Mouse Anti-SLAMF8 (AA 23-233) Recombinant Antibody (CBXS-0425) (CBMAB-S3376-CQ)

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Target: SLAMF8
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBXS-0425
Application*: E, F
Datasheet SDS

Mouse Anti-SLAMF8 Recombinant Antibody (CBXS-0424) (CBMAB-S3375-CQ)

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Target: SLAMF8
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: CBXS-0424
Application*: E
Datasheet SDS

Rabbit Anti-SLAMF8 Recombinant Antibody (CBXS-4284) (CBMAB-S1530-CQ)

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Target: SLAMF8
Host: Rabbit
Antibody Isotype: IgG
Specificity: Mouse
Clone: CBXS-4284
Application*: P
Datasheet SDS

Rabbit Anti-SLAMF8 Recombinant Antibody (CBXS-4264) (CBMAB-S1514-CQ)

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Target: SLAMF8
Host: Rabbit
Antibody Isotype: IgG
Specificity: Mouse
Clone: CBXS-4264
Application*: E
Datasheet SDS

Human Anti-SLAMF8 Recombinant Antibody (CBXC-0838) (CBMAB-C5834-CQ)

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Target: SLAMF8
Host: Human
Antibody Isotype: IgG1
Specificity: Human
Clone: CBXC-0838
Application*: F
Datasheet SDS
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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IGImmunochromatography
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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