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Human Anti-SLAMF8 Recombinant Antibody (CBXC-0838) (CBMAB-C5834-CQ)

This product is a recombinant human antibody that recognizes SLAMF8. The antibody CBXC-0838 can be used for immunoassay techniques such as: FC.
See all SLAMF8 antibodies

Summary

Host Animal
Human
Specificity
Human
Clone
CBXC-0838
Antibody Isotype
IgG1
Application
FC

Basic Information

Specificity
Human
Antibody Isotype
IgG1
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
Buffer containing stabilizer
Preservative
0.05% sodium azide
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
SLAM Family Member 8
Introduction
This gene encodes a member of the CD2 family of cell surface proteins involved in lymphocyte activation. These proteins are characterized by Ig domains. This protein is expressed in lymphoid tissues, and studies of a similar protein in mouse suggest that it may function during B cell lineage commitment. The gene is found in a region of chromosome 1 containing many CD2 genes.
Entrez Gene ID
56833
UniProt ID
Q9P0V8
Alternative Names
SLAM Family Member 8; BCM-Like Membrane Protein; BLAME; B Lymphocyte Activator Macrophage Expressed; B-Lymphocyte Activator Macrophage Expressed; CD353 Antigen; SBBI42; CD353;
Function
May play a role in B-lineage commitment and/or modulation of signaling through the B-cell receptor.
Biological Process
Biological Process B-1 B cell lineage commitmentBy SimilarityISS:UniProtKB
Biological Process defense response to bacteriumISS:UniProtKB
Biological Process leukocyte chemotaxis involved in inflammatory responseISS:UniProtKB
Biological Process negative regulation of dendritic cell chemotaxisISS:UniProtKB
Biological Process negative regulation of macrophage chemotaxisISS:UniProtKB
Biological Process negative regulation of monocyte chemotaxisISS:UniProtKB
Biological Process negative regulation of neutrophil migrationISS:UniProtKB
Biological Process negative regulation of respiratory burst involved in inflammatory responseISS:UniProtKB
Biological Process phagosome acidificationISS:UniProtKB
Biological Process regulation of B cell differentiationBy SimilarityISS:UniProtKB
Biological Process regulation of kinase activityISS:UniProtKB
Biological Process regulation of NAD(P)H oxidase activityISS:UniProtKB
Cellular Location
Membrane
Topology
Extracellular: 23-233
Helical: 234-254
Cytoplasmic: 255-285
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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