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Rabbit Anti-SLAMF8 Recombinant Antibody (CBXS-4264) (CBMAB-S1514-CQ)


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Summary

Host Animal
Rabbit
Specificity
Mouse
Clone
CBXS-4264
Antibody Isotype
IgG
Application
ELISA

Basic Information

Immunogen
Recombinant Mouse SLAMF8 protein
Specificity
Mouse
Antibody Isotype
IgG
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
SLAM Family Member 8
Introduction
This gene encodes a member of the CD2 family of cell surface proteins involved in lymphocyte activation. These proteins are characterized by Ig domains. This protein is expressed in lymphoid tissues, and studies of a similar protein in mouse suggest that it may function during B cell lineage commitment. The gene is found in a region of chromosome 1 containing many CD2 genes.
Entrez Gene ID
74748
UniProt ID
Q9D3G2
Alternative Names
5830408F06Rik; Blame; SBBI42
Function
May play a role in B-lineage commitment and/or modulation of signaling through the B-cell receptor.
Biological Process
Biological Process B-1 B cell lineage commitmentBy SimilarityISS:UniProtKB
Biological Process defense response to bacteriumISS:UniProtKB
Biological Process leukocyte chemotaxis involved in inflammatory responseISS:UniProtKB
Biological Process negative regulation of dendritic cell chemotaxisISS:UniProtKB
Biological Process negative regulation of macrophage chemotaxisISS:UniProtKB
Biological Process negative regulation of monocyte chemotaxisISS:UniProtKB
Biological Process negative regulation of neutrophil migrationISS:UniProtKB
Biological Process negative regulation of respiratory burst involved in inflammatory responseISS:UniProtKB
Biological Process phagosome acidificationISS:UniProtKB
Biological Process regulation of B cell differentiationBy SimilarityISS:UniProtKB
Biological Process regulation of kinase activityISS:UniProtKB
Biological Process regulation of NAD(P)H oxidase activityISS:UniProtKB
Cellular Location
Membrane
Topology
Extracellular: 23-233
Helical: 234-254
Cytoplasmic: 255-285
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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