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SLC6A11

Gamma-aminobutyric acid (GABA) is a major inhibitory neurotransmitter. GABAergic neurotransmission is terminated by the uptake of GABA into the presynaptic terminal and the surrounding astroglial cells by sodium-dependent transporters, such as SLC6A11.[supplied by OMIM

Full Name

solute carrier family 6 (neurotransmitter transporter, GABA), member 11

Function

Mediates sodium- and chloride-dependent transport of gamma-aminobutyric acid (GABA) (PubMed:7874447).
Can also mediate transport of beta-alanine and to a lower extent that of taurine and hypotaurine (By similarity).

Biological Process

Biological Process brain developmentIEA:Ensembl
Biological Process gamma-aminobutyric acid reuptakeTAS:Reactome
Biological Process monocarboxylic acid transportManual Assertion Based On ExperimentIDA:ARUK-UCL
Biological Process response to xenobiotic stimulusIEA:Ensembl
Biological Process sodium ion transmembrane transportManual Assertion Based On ExperimentIBA:GO_Central

Cellular Location

Cell membrane

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Anti-SLC6A11 antibodies

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Mouse Anti-SLC6A11 Recombinant Antibody (2C3) (CBMAB-A8251-LY)

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Target: SLC6A11

Host: Mouse

Antibody Isotype: IgG2a, κ

Specificity: Human

Clone: 2C3

Application*: WB, E

Mouse Anti-SLC6A11 Recombinant Antibody (CBXS-0991) (CBMAB-S3896-CQ)

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Target: SLC6A11

Host: Mouse

Antibody Isotype: IgG1, κ

Specificity: Human

Clone: CBXS-0991

Application*: E, WB

Mouse Anti-SLC6A11 Recombinant Antibody (CBXS-0990) (CBMAB-S3895-CQ)

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Target: SLC6A11

Host: Mouse

Antibody Isotype: IgG2a, κ

Specificity: Human

Clone: CBXS-0990

Application*: SE, E, WB

Mouse Anti-SLC6A11 Recombinant Antibody (CBXS-4436) (CBMAB-S1678-CQ)

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Target: SLC6A11

Host: Mouse

Antibody Isotype: IgG2a, κ

Specificity: Human

Clone: CBXS-4436

Application*: E, WB

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(P): Predicted

* Abbreviations

AActivation
AGAgonist
APApoptosis
BBlocking
BABioassay
BIBioimaging
CImmunohistochemistry-Frozen Sections
CIChromatin Immunoprecipitation
CTCytotoxicity
CSCostimulation
DDepletion
DBDot Blot

EELISA
ECELISA(Cap)
EDELISA(Det)
ESELISpot
EMElectron Microscopy
FFlow Cytometry
FNFunction Assay
GSGel Supershift
IInhibition
IAEnzyme Immunoassay
ICImmunocytochemistry
IDImmunodiffusion
IEImmunoelectrophoresis

IFImmunofluorescence
IGImmunochromatography
IHImmunohistochemistry
IMImmunomicroscopy
IOImmunoassay
IPImmunoprecipitation
ISIntracellular Staining for Flow Cytometry
LALuminex Assay
LFLateral Flow Immunoassay
MMicroarray
MCMass Cytometry/CyTOF
MDMeDIP

MSElectrophoretic Mobility Shift Assay
NNeutralization
PImmunohistologyp-Paraffin Sections
PAPeptide Array
PEPeptide ELISA
PLProximity Ligation Assay
RRadioimmunoassay
SStimulation
SESandwich ELISA
SHIn situ hybridization
TCTissue Culture
WBWestern Blot

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