SLC6A11

Gamma-aminobutyric acid (GABA) is a major inhibitory neurotransmitter. GABAergic neurotransmission is terminated by the uptake of GABA into the presynaptic terminal and the surrounding astroglial cells by sodium-dependent transporters, such as SLC6A11.[supplied by OMIM

Full Name

solute carrier family 6 (neurotransmitter transporter, GABA), member 11

Function

Mediates sodium- and chloride-dependent transport of gamma-aminobutyric acid (GABA) (PubMed:7874447).
Can also mediate transport of beta-alanine and to a lower extent that of taurine and hypotaurine (By similarity).

Biological Process

Biological Process brain developmentIEA:Ensembl
Biological Process gamma-aminobutyric acid reuptakeTAS:Reactome
Biological Process monocarboxylic acid transportManual Assertion Based On ExperimentIDA:ARUK-UCL
Biological Process response to xenobiotic stimulusIEA:Ensembl
Biological Process sodium ion transmembrane transportManual Assertion Based On ExperimentIBA:GO_Central

Cellular Location

Cell membrane

Anti-SLC6A11 antibodies

Mouse Anti-SLC6A11 Recombinant Antibody (2C3) (CBMAB-A8251-LY)

Datasheet

SDS

Target: SLC6A11

Host: Mouse

Antibody Isotype: IgG2a, κ

Specificity: Human

Clone: 2C3

Application*: WB, E

Mouse Anti-SLC6A11 Recombinant Antibody (CBXS-4436) (CBMAB-S1678-CQ)

Datasheet

SDS

Target: SLC6A11

Host: Mouse

Antibody Isotype: IgG2a, κ

Specificity: Human

Clone: CBXS-4436

Application*: E, WB

Mouse Anti-SLC6A11 Recombinant Antibody (CBXS-0990) (CBMAB-S3895-CQ)

Datasheet

SDS

Target: SLC6A11

Host: Mouse

Antibody Isotype: IgG2a, κ

Specificity: Human

Clone: CBXS-0990

Application*: SE, E, WB

Mouse Anti-SLC6A11 Recombinant Antibody (CBXS-0991) (CBMAB-S3896-CQ)

Datasheet

SDS

Target: SLC6A11

Host: Mouse

Antibody Isotype: IgG1, κ

Specificity: Human

Clone: CBXS-0991

Application*: E, WB

For Research Use Only. Not For Clinical Use.

(P): Predicted

* Abbreviations

IFImmunofluorescence

IHImmunohistochemistry

IPImmunoprecipitation

WBWestern Blot

EELISA

MMicroarray

CIChromatin Immunoprecipitation

FFlow Cytometry

FNFunction Assay

IDImmunodiffusion

RRadioimmunoassay

TCTissue Culture

GSGel Supershift

NNeutralization

BBlocking

AActivation

IInhibition

DDepletion

ESELISpot

DBDot Blot

MCMass Cytometry/CyTOF

CTCytotoxicity

SStimulation

AGAgonist

APApoptosis

IMImmunomicroscopy

BABioassay

CSCostimulation

EMElectron Microscopy

IEImmunoelectrophoresis

PAPeptide Array

ICImmunocytochemistry

PEPeptide ELISA

MDMeDIP

SHIn situ hybridization

IAEnzyme Immunoassay

SEsandwich ELISA

PLProximity Ligation Assay

ECELISA(Cap)

EDELISA(Det)

BIBioimaging

IOImmunoassay

LFLateral Flow Immunoassay

LALuminex Assay

CImmunohistochemistry-Frozen Sections

PImmunohistologyp-Paraffin Sections

ISIntracellular Staining for Flow Cytometry

MSElectrophoretic Mobility Shift Assay

RIRNA Binding Protein Immunoprecipitation (RIP)