Mouse Anti-SLC6A11 Recombinant Antibody (CBXS-0990) (CBMAB-S3895-CQ)

Name: Mouse Anti-SLC6A11 Recombinant Antibody (CBXS-0990)
SKU: CBMAB-S3895-CQ
Rating: 5 (1 reviews)

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Datasheet

SDS

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Basic Information

Host Animal

Mouse

Clone

CBXS-0990

Application

S-ELISA, ELISA, WB

Immunogen

SLC6A11 (NP_055044.1, 164 a.a.-225 a.a) partial recombinant protein with GST tag

Specificity

Human

Antibody Isotype

IgG2a, κ

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Liquid

Buffer

PBS, pH 7.2

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

More Infomation

Target

Full Name

solute carrier family 6 (neurotransmitter transporter, GABA), member 11

Introduction

The protein encoded by this gene is a sodium-dependent transporter that uptakes gamma-aminobutyric acid (GABA), an inhibitory neurotransmitter, which ends the GABA neurotransmission. Defects in this gene may result in epilepsy, behavioral problems, or intellectual problems. Two transcript variants encoding different isoforms have been found for this gene.

Entrez Gene ID

6538

UniProt ID

P48066

Alternative Names

Solute Carrier Family 6 Member 11; Solute Carrier Family 6 (Neurotransmitter Transporter, GABA), Member 11; Solute Carrier Family 6 (Neurotransmitter Transporter), Member 11; GABA Transporter 3; GAT-3; GAT3; Sodium- And Chloride-Dependent GABA Transporter 3; GABT3; GAT4;

Function

Mediates sodium- and chloride-dependent transport of gamma-aminobutyric acid (GABA) (PubMed:7874447).
Can also mediate transport of beta-alanine and to a lower extent that of taurine and hypotaurine (By similarity).

Biological Process

Biological Process brain developmentIEA:Ensembl
Biological Process gamma-aminobutyric acid reuptakeTAS:Reactome
Biological Process monocarboxylic acid transportManual Assertion Based On ExperimentIDA:ARUK-UCL
Biological Process response to xenobiotic stimulusIEA:Ensembl
Biological Process sodium ion transmembrane transportManual Assertion Based On ExperimentIBA:GO_Central

Cellular Location

Cell membrane

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

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Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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