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Mouse Anti-SLC6A11 Recombinant Antibody (CBXS-4436) (CBMAB-S1678-CQ)

This product is a mouse antibody that recognizes SLC6A11. The antibody CBXS-4436 can be used for immunoassay techniques such as: ELISA, WB.
See all SLC6A11 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
CBXS-4436
Antibody Isotype
IgG2a, κ
Application
ELISA, WB

Basic Information

Specificity
Human
Antibody Isotype
IgG2a, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS, pH 7.2
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
solute carrier family 6 (neurotransmitter transporter, GABA), member 11
Introduction
The protein encoded by this gene is a sodium-dependent transporter that uptakes gamma-aminobutyric acid (GABA), an inhibitory neurotransmitter, which ends the GABA neurotransmission. Defects in this gene may result in epilepsy, behavioral problems, or intellectual problems. Two transcript variants encoding different isoforms have been found for this gene.
Entrez Gene ID
6538
UniProt ID
P48066
Alternative Names
Solute Carrier Family 6 Member 11; Solute Carrier Family 6 (Neurotransmitter Transporter, GABA), Member 11; Solute Carrier Family 6 (Neurotransmitter Transporter), Member 11; GABA Transporter 3; GAT-3; GAT3; Sodium- And Chloride-Dependent GABA Transporter 3; GABT3; GAT4;
Function
Mediates sodium- and chloride-dependent transport of gamma-aminobutyric acid (GABA) (PubMed:7874447).
Can also mediate transport of beta-alanine and to a lower extent that of taurine and hypotaurine (By similarity).
Biological Process
Biological Process brain developmentIEA:Ensembl
Biological Process gamma-aminobutyric acid reuptakeTAS:Reactome
Biological Process monocarboxylic acid transportManual Assertion Based On ExperimentIDA:ARUK-UCL
Biological Process response to xenobiotic stimulusIEA:Ensembl
Biological Process sodium ion transmembrane transportManual Assertion Based On ExperimentIBA:GO_Central
Cellular Location
Cell membrane
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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