SMYD1
SMYD1 (SET And MYND Domain Containing 1) is a Protein Coding gene. Among its related pathways are Heart Development and PKMTs methylate histone lysines. Gene Ontology (GO) annotations related to this gene include transcription corepressor activity and histone-lysine N-methyltransferase activity. An important paralog of this gene is SMYD2.
Full Name
SET And MYND Domain Containing 1
Function
Methylates histone H3 at 'Lys-4' (H3K4me), seems able to perform both mono-, di-, and trimethylation. Acts as a transcriptional repressor. Essential for cardiomyocyte differentiation and cardiac morphogenesis.
Biological Process
Biological Process chromatin remodelingIEA:Ensembl
Biological Process heart developmentIEA:Ensembl
Biological Process histone lysine methylationManual Assertion Based On ExperimentIBA:GO_Central
Biological Process positive regulation of myoblast differentiationManual Assertion Based On ExperimentIDA:BHF-UCL
Biological Process positive regulation of myotube differentiationManual Assertion Based On ExperimentIDA:BHF-UCL
Biological Process skeletal muscle cell differentiationIEA:Ensembl
Biological Process heart developmentIEA:Ensembl
Biological Process histone lysine methylationManual Assertion Based On ExperimentIBA:GO_Central
Biological Process positive regulation of myoblast differentiationManual Assertion Based On ExperimentIDA:BHF-UCL
Biological Process positive regulation of myotube differentiationManual Assertion Based On ExperimentIDA:BHF-UCL
Biological Process skeletal muscle cell differentiationIEA:Ensembl
Cellular Location
Cytoplasm
Nucleus
Nucleus
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Anti-SMYD1 antibodies
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CompareTarget: SMYD1
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: CB67A
Application*: ELISA, WB
Target: SMYD1
Host: Mouse
Antibody Isotype: IgG
Specificity: Rat
Clone: CBAb223
Application*: WB
Target: SMYD1
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Rat
Clone: 2E11-B6-C7
Application*: WB
Target: SMYD1
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: 3H11
Application*: E, WB
Target: SMYD1
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Rat
Clone: CBXS-6094
Application*: WB, E
Target: SMYD1
Host: Mouse
Specificity: Human, Rat
Clone: CBXS-2601
Application*: WB
Target: SMYD1
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Rat
Clone: CBXS-2514
Application*: WB
Target: SMYD1
Host: Mouse
Specificity: Human
Clone: CBXS-2121
Application*: WB, IP, IF, E
Target: SMYD1
Host: Mouse
Specificity: Human
Clone: CBXS-2012
Application*: WB, IP, IF, E
Target: SMYD1
Host: Rabbit
Antibody Isotype: IgG
Specificity: Mouse, Rat, Human
Clone: CBXS-1360
Application*: WB, IP, P
Target: SMYD1
Host: Rabbit
Antibody Isotype: IgG
Specificity: Mouse, Rat, Human
Clone: CBXS-1359
Application*: WB
Target: SMYD1
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: CBXS-0583
Application*: WB
Target: SMYD1
Host: Mouse
Specificity: Human
Clone: CBXS-0582
Application*: WB
Target: SMYD1
Host: Mouse
Specificity: Rat
Clone: CBXS-0581
Application*: WB
Target: SMYD1
Host: Mouse
Specificity: Mouse, Rat
Clone: CBXS-0580
Application*: WB
Target: SMYD1
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Rat
Clone: CBXS-4524
Application*: WB
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For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
- AActivation
- AGAgonist
- APApoptosis
- BBlocking
- BABioassay
- BIBioimaging
- CImmunohistochemistry-Frozen Sections
- CIChromatin Immunoprecipitation
- CTCytotoxicity
- CSCostimulation
- DDepletion
- DBDot Blot
- EELISA
- ECELISA(Cap)
- EDELISA(Det)
- ESELISpot
- EMElectron Microscopy
- FFlow Cytometry
- FNFunction Assay
- GSGel Supershift
- IInhibition
- IAEnzyme Immunoassay
- ICImmunocytochemistry
- IDImmunodiffusion
- IEImmunoelectrophoresis
- IFImmunofluorescence
- IGImmunochromatography
- IHImmunohistochemistry
- IMImmunomicroscopy
- IOImmunoassay
- IPImmunoprecipitation
- ISIntracellular Staining for Flow Cytometry
- LALuminex Assay
- LFLateral Flow Immunoassay
- MMicroarray
- MCMass Cytometry/CyTOF
- MDMeDIP
- MSElectrophoretic Mobility Shift Assay
- NNeutralization
- PImmunohistologyp-Paraffin Sections
- PAPeptide Array
- PEPeptide ELISA
- PLProximity Ligation Assay
- RRadioimmunoassay
- SStimulation
- SESandwich ELISA
- SHIn situ hybridization
- TCTissue Culture
- WBWestern Blot
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