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Recombinant Mouse Anti-SMYD1 Antibody (CBAb223) (CBMAB-Ab223-LY)


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Summary

Host Animal
Mouse
Specificity
Rat
Clone
CBAb223
Antibody Isotype
IgG
Application
WB 1:100-1:200

Basic Information

Immunogen
Recombinant protein of human SMYD1
Specificity
Rat
Antibody Isotype
IgG
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
50% glycerol
Preservative
0.02% sodium azide
Purity
> 95% Purity determined by SDS-PAGE.
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
SET And MYND Domain Containing 1
Entrez Gene ID
297333
UniProt ID
D4A3D2
Alternative Names
SMYD1; BOP; KMT3D; ZMYND18; ZMYND22; SET and MYND domain containing 1
Function
Methylates histone H3 at 'Lys-4' (H3K4me), seems able to perform both mono-, di-, and trimethylation. Acts as a transcriptional repressor. Essential for cardiomyocyte differentiation and cardiac morphogenesis.
Biological Process
Biological Process chromatin remodelingIEA:Ensembl
Biological Process heart developmentIEA:Ensembl
Biological Process histone lysine methylationManual Assertion Based On ExperimentIBA:GO_Central
Biological Process positive regulation of myoblast differentiationManual Assertion Based On ExperimentIDA:BHF-UCL
Biological Process positive regulation of myotube differentiationManual Assertion Based On ExperimentIDA:BHF-UCL
Biological Process skeletal muscle cell differentiationIEA:Ensembl
Cellular Location
Cytoplasm
Nucleus
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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