Rabbit Anti-SMYD1 Recombinant Antibody (CBXS-1359) (CBMAB-S4217-CQ)

Name: Rabbit Anti-SMYD1 Recombinant Antibody (CBXS-1359)
SKU: CBMAB-S4217-CQ
Rating: 5 (1 reviews)

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Datasheet

SDS

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Basic Information

Host Animal

Rabbit

Clone

CBXS-1359

Application

Specificity

Mouse, Rat, Human

Antibody Isotype

IgG

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Concentration

1 mg/mL

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

More Infomation

Target

Full Name

SET And MYND Domain Containing 1

Introduction

SMYD1 (SET And MYND Domain Containing 1) is a Protein Coding gene. Among its related pathways are Heart Development and PKMTs methylate histone lysines. Gene Ontology (GO) annotations related to this gene include transcription corepressor activity and histone-lysine N-methyltransferase activity. An important paralog of this gene is SMYD2.

Entrez Gene ID

Human	150572
Mouse	12180
Rat	297333

UniProt ID

Human	Q8NB12
Mouse	P97443
Rat	D4A3D2

Alternative Names

SET And MYND Domain Containing 1; SET And MYND Domain-Containing Protein 1; Histone-Lysine N-Methyltransferase SMYD1; Zinc Finger, MYND Domain Containing 18; CD8 Beta Opposite; EC 2.1.1.43;

Function

Methylates histone H3 at 'Lys-4' (H3K4me), seems able to perform both mono-, di-, and trimethylation. Acts as a transcriptional repressor. Essential for cardiomyocyte differentiation and cardiac morphogenesis.

Biological Process

Biological Process chromatin remodelingIEA:Ensembl
Biological Process heart developmentIEA:Ensembl
Biological Process histone lysine methylationManual Assertion Based On ExperimentIBA:GO_Central
Biological Process positive regulation of myoblast differentiationManual Assertion Based On ExperimentIDA:BHF-UCL
Biological Process positive regulation of myotube differentiationManual Assertion Based On ExperimentIDA:BHF-UCL
Biological Process skeletal muscle cell differentiationIEA:Ensembl

Cellular Location

Cytoplasm
Nucleus

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

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Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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