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Rabbit Anti-SMYD1 Recombinant Antibody (CBXS-1359) (CBMAB-S4217-CQ)


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Summary

Host Animal
Rabbit
Specificity
Mouse, Rat, Human
Clone
CBXS-1359
Antibody Isotype
IgG
Application
WB

Basic Information

Specificity
Mouse, Rat, Human
Antibody Isotype
IgG
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Concentration
1 mg/mL
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
SET And MYND Domain Containing 1
Introduction
SMYD1 (SET And MYND Domain Containing 1) is a Protein Coding gene. Among its related pathways are Heart Development and PKMTs methylate histone lysines. Gene Ontology (GO) annotations related to this gene include transcription corepressor activity and histone-lysine N-methyltransferase activity. An important paralog of this gene is SMYD2.
Entrez Gene ID
Human150572
Mouse12180
Rat297333
UniProt ID
HumanQ8NB12
MouseP97443
RatD4A3D2
Alternative Names
SET And MYND Domain Containing 1; SET And MYND Domain-Containing Protein 1; Histone-Lysine N-Methyltransferase SMYD1; Zinc Finger, MYND Domain Containing 18; CD8 Beta Opposite; EC 2.1.1.43;
Function
Methylates histone H3 at 'Lys-4' (H3K4me), seems able to perform both mono-, di-, and trimethylation. Acts as a transcriptional repressor. Essential for cardiomyocyte differentiation and cardiac morphogenesis.
Biological Process
Biological Process chromatin remodelingIEA:Ensembl
Biological Process heart developmentIEA:Ensembl
Biological Process histone lysine methylationManual Assertion Based On ExperimentIBA:GO_Central
Biological Process positive regulation of myoblast differentiationManual Assertion Based On ExperimentIDA:BHF-UCL
Biological Process positive regulation of myotube differentiationManual Assertion Based On ExperimentIDA:BHF-UCL
Biological Process skeletal muscle cell differentiationIEA:Ensembl
Cellular Location
Cytoplasm
Nucleus
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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