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SNRPB2

The protein encoded by this gene associates with stem loop IV of U2 small nuclear ribonucleoprotein (U2 snRNP) in the presence of snRNP-A'. The encoded protein may play a role in pre-mRNA splicing. Autoantibodies from patients with systemic lupus erythematosus frequently recognize epitopes on the encoded protein. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq]
Full Name
small nuclear ribonucleoprotein polypeptide B''
Function
Involved in pre-mRNA splicing as component of the spliceosome (PubMed:11991638, PubMed:28502770, PubMed:28781166, PubMed:28076346).
Associated with sn-RNP U2, where it contributes to the binding of stem loop IV of U2 snRNA (PubMed:9716128).
Biological Process
Biological Process mRNA splicing, via spliceosomeManual Assertion Based On ExperimentIDA:UniProtKB
Biological Process U2-type prespliceosome assembly1 PublicationIC:ComplexPortal
Cellular Location
Nucleus

Anti-SNRPB2 antibodies

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Target: SNRPB2
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: 2F4
Application*: SE, E
Target: SNRPB2
Host: Mouse
Specificity: Mouse, Rat, Human
Clone: CBFYS-005
Application*: WB, IP, IF, E
Target: SNRPB2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBFYS-006
Application*: IF, IP, WB
Target: SNRPB2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBXS-5599
Application*: P, WB
Target: SNRPB2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBXS-4897
Application*: WB
Target: SNRPB2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBXS-4742
Application*: IC, IF, WB
Target: SNRPB2
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: CBXS-4586
Application*: E
Target: SNRPB2
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: CBXS-4556
Application*: IC, IF, WB
Target: SNRPB2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBXS-4353
Application*: WB, IH
Target: SNRPB2
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: CBXS-4082
Application*: WB
Target: SNRPB2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBXS-3877
Application*: WB
For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
IFImmunofluorescence
IHImmunohistochemistry
IPImmunoprecipitation
WBWestern Blot
EELISA
MMicroarray
CIChromatin Immunoprecipitation
FFlow Cytometry
FNFunction Assay
IDImmunodiffusion
RRadioimmunoassay
TCTissue Culture
GSGel Supershift
NNeutralization
BBlocking
AActivation
IInhibition
DDepletion
ESELISpot
DBDot Blot
MCMass Cytometry/CyTOF
CTCytotoxicity
SStimulation
AGAgonist
APApoptosis
IMImmunomicroscopy
BABioassay
CSCostimulation
EMElectron Microscopy
IEImmunoelectrophoresis
PAPeptide Array
ICImmunocytochemistry
PEPeptide ELISA
MDMeDIP
SHIn situ hybridization
IAEnzyme Immunoassay
SEsandwich ELISA
PLProximity Ligation Assay
ECELISA(Cap)
EDELISA(Det)
BIBioimaging
IOImmunoassay
LFLateral Flow Immunoassay
LALuminex Assay
CImmunohistochemistry-Frozen Sections
PImmunohistologyp-Paraffin Sections
ISIntracellular Staining for Flow Cytometry
MSElectrophoretic Mobility Shift Assay
RIRNA Binding Protein Immunoprecipitation (RIP)
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