SNRPB2

The protein encoded by this gene associates with stem loop IV of U2 small nuclear ribonucleoprotein (U2 snRNP) in the presence of snRNP-A'. The encoded protein may play a role in pre-mRNA splicing. Autoantibodies from patients with systemic lupus erythematosus frequently recognize epitopes on the encoded protein. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq]
Full Name
small nuclear ribonucleoprotein polypeptide B''
Function
Involved in pre-mRNA splicing as component of the spliceosome (PubMed:11991638, PubMed:28502770, PubMed:28781166, PubMed:28076346).
Associated with sn-RNP U2, where it contributes to the binding of stem loop IV of U2 snRNA (PubMed:9716128).
Biological Process
Biological Process mRNA splicing, via spliceosomeManual Assertion Based On ExperimentIDA:UniProtKB
Biological Process U2-type prespliceosome assembly1 PublicationIC:ComplexPortal
Cellular Location
Nucleus
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Anti-SNRPB2 antibodies

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Mouse Anti-SNRPB2 Recombinant Antibody (2F4) (CBMAB-A8425-LY)

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Target: SNRPB2
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: 2F4
Application*: SE, E
Datasheet SDS

Mouse Anti-SNRPB2 Recombinant Antibody (CBXS-4897) (CBMAB-S2119-CQ)

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Target: SNRPB2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBXS-4897
Application*: WB
Datasheet SDS

Mouse Anti-SNRPB2 Recombinant Antibody (CBXS-4742) (CBMAB-S1971-CQ)

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Target: SNRPB2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBXS-4742
Application*: IC, IF, WB
Datasheet SDS

Mouse Anti-SNRPB2 Recombinant Antibody (CBXS-4586) (CBMAB-S1826-CQ)

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Target: SNRPB2
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: CBXS-4586
Application*: E
Datasheet SDS

Mouse Anti-SNRPB2 Recombinant Antibody (CBXS-4556) (CBMAB-S1796-CQ)

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Target: SNRPB2
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: CBXS-4556
Application*: IC, IF, WB
Datasheet SDS

Mouse Anti-SNRPB2 Recombinant Antibody (CBXS-4353) (CBMAB-S1597-CQ)

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Target: SNRPB2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBXS-4353
Application*: WB, IH
Datasheet SDS

Mouse Anti-SNRPB2 Recombinant Antibody (CBXS-4082) (CBMAB-S1340-CQ)

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Target: SNRPB2
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: CBXS-4082
Application*: WB
Datasheet SDS

Mouse Anti-SNRPB2 Recombinant Antibody (CBXS-3877) (CBMAB-S1146-CQ)

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Target: SNRPB2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBXS-3877
Application*: WB
Datasheet SDS

Mouse Anti-SNRPB2 Recombinant Antibody (CBXS-5599) (CBMAB-S0477-CQ)

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Target: SNRPB2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBXS-5599
Application*: P, WB
Datasheet SDS

Mouse Anti-SNRPB2 Recombinant Antibody (CBFYS-006) (CBMAB-S0006-FY)

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Target: SNRPB2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBFYS-006
Application*: IF, IP, WB
Datasheet SDS

Mouse Anti-SNRPB2 Recombinant Antibody (CBFYS-005) (CBMAB-S0005-FY)

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Target: SNRPB2
Host: Mouse
Specificity: Mouse, Rat, Human
Clone: CBFYS-005
Application*: WB, IP, IF, E
Datasheet SDS
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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IGImmunochromatography
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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