SNUPN

The nuclear import of the spliceosomal snRNPs U1, U2, U4 and U5, is dependent on the presence of a complex nuclear localization signal. The latter is composed of the 5'-2,2,7-terminal trimethylguanosine (m3G) cap structure of the U snRNA and the Sm core domain. The protein encoded by this gene interacts specifically with m3G-cap and functions as an snRNP-specific nuclear import receptor. Alternatively spliced transcript variants encoding the same protein have been identified for this gene. [provided by RefSeq, Jul 2008]
Full Name
Snurportin 1
Function
Functions as an U snRNP-specific nuclear import adapter. Involved in the trimethylguanosine (m3G)-cap-dependent nuclear import of U snRNPs. Binds specifically to the terminal m3G-cap U snRNAs.
Biological Process
Biological Process protein import into nucleusIEA:InterPro
Biological Process RNA import into nucleusManual Assertion Based On ExperimentIDA:ComplexPortal
Biological Process snRNA import into nucleusIEA:InterPro
Cellular Location
Nucleus
Cytoplasm
Nucleoplasmic shuttling protein. Its nuclear import involves the nucleocytoplasmic transport receptor importin beta (PubMed:10209022, PubMed:12095920).
It is re-exported to the cytoplasm by the XPO1-dependent nuclear export receptor pathway (PubMed:10209022).
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Anti-SNUPN antibodies

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SNUPN Matched Antibody Pair (1116) (APMAB-1116LY)

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Target: SNUPN
Specificity: Human
Datasheet SDS

Mouse Anti-SNUPN Recombinant Antibody (2B2-1B4) (CBMAB-A7689-LY)

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Target: SNUPN
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: 2B2-1B4
Application*: WB, E
Datasheet SDS

Mouse Anti-SNUPN Recombinant Antibody (CBXS-2843) (CBMAB-S5593-CQ)

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Target: SNUPN
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: CBXS-2843
Application*: E, IF, WB
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Mouse Anti-SNUPN Recombinant Antibody (CBXS-0620) (CBMAB-S3561-CQ)

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Target: SNUPN
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: CBXS-0620
Application*: E, WB, IF
Datasheet SDS
More Infomation
Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized) Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)

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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IGImmunochromatography
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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