SPON1

SPON1 (Spondin 1) is a Protein Coding gene. Diseases associated with SPON1 include Peters-Plus Syndrome. Among its related pathways are Apoptotic Pathways in Synovial Fibroblasts and PAK Pathway. An important paralog of this gene is SPON2.

Full Name

Spondin 1

Function

Cell adhesion protein that promotes the attachment of spinal cord and sensory neuron cells and the outgrowth of neurites in vitro. May contribute to the growth and guidance of axons in both the spinal cord and the PNS (By similarity).
Major factor for vascular smooth muscle cell.

Biological Process

Biological Process cell adhesionManual Assertion Based On ExperimentIBA:GO_Central
Biological Process negative regulation of amyloid-beta formationIEA:Ensembl
Biological Process positive regulation of amyloid precursor protein catabolic processIEA:Ensembl
Biological Process positive regulation of protein bindingIEA:Ensembl
Biological Process positive regulation of protein processingIEA:Ensembl
Biological Process protein processingIEA:Ensembl

Cellular Location

Secreted, extracellular space, extracellular matrix