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Mouse Anti-SPON1 Recombinant Antibody (CBXS-3097) (CBMAB-S5842-CQ)


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Summary

Host Animal
Mouse
Specificity
Human
Clone
CBXS-3097
Antibody Isotype
IgG1, κ
Application
ELISA

Basic Information

Immunogen
Partial recombinant corresponding to aa699-806 from SPON1 (NP_006099) with GST tag
Specificity
Human
Antibody Isotype
IgG1, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS, pH 7.2
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
Spondin 1
Introduction
SPON1 (Spondin 1) is a Protein Coding gene. Diseases associated with SPON1 include Peters-Plus Syndrome. Among its related pathways are Apoptotic Pathways in Synovial Fibroblasts and PAK Pathway. An important paralog of this gene is SPON2.
Entrez Gene ID
10418
UniProt ID
Q9HCB6
Alternative Names
Spondin 1; Spondin 1, (F-Spondin) Extracellular Matrix Protein; Vascular Smooth Muscle Cell Growth-Promoting Factor; F-Spondin; Spondin 1, Extracellular Matrix Protein; VSGP/F-Spondin; Spondin-1; KIAA0762; VSGP;
Function
Cell adhesion protein that promotes the attachment of spinal cord and sensory neuron cells and the outgrowth of neurites in vitro. May contribute to the growth and guidance of axons in both the spinal cord and the PNS (By similarity).
Major factor for vascular smooth muscle cell.
Biological Process
Biological Process cell adhesionManual Assertion Based On ExperimentIBA:GO_Central
Biological Process negative regulation of amyloid-beta formationIEA:Ensembl
Biological Process positive regulation of amyloid precursor protein catabolic processIEA:Ensembl
Biological Process positive regulation of protein bindingIEA:Ensembl
Biological Process positive regulation of protein processingIEA:Ensembl
Biological Process protein processingIEA:Ensembl
Cellular Location
Secreted, extracellular space, extracellular matrix
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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