SRPK3

This gene encodes a protein kinase similar to a protein kinase which is specific for the SR (serine/arginine-rich domain) family of splicing factors. A highly similar protein has been shown to play a role in muscle development in mice. Multiple transcript variants encoding different isoforms have been found for this gene.

SRSF Protein Kinase 3

Serine/arginine-rich protein-specific kinase which specifically phosphorylates its substrates at serine residues located in regions rich in arginine/serine dipeptides, known as RS domains. Phosphorylates the SR splicing factor SRSF1 and the lamin-B receptor (LBR) in vitro. Required for normal muscle development (By similarity).

Biological Process cell differentiationIEA:UniProtKB-KW
Biological Process intracellular signal transductionManual Assertion Based On ExperimentIBA:GO_Central
Biological Process muscle tissue developmentISS:UniProtKB
Biological Process protein phosphorylationIEA:Ensembl
Biological Process regulation of mRNA processingManual Assertion Based On ExperimentIBA:GO_Central
Biological Process skeletal muscle tissue developmentIEA:Ensembl
Biological Process spliceosomal complex assemblyManual Assertion Based On ExperimentIBA:GO_Central

cytoplasm
nucleus