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SRPK3

This gene encodes a protein kinase similar to a protein kinase which is specific for the SR (serine/arginine-rich domain) family of splicing factors. A highly similar protein has been shown to play a role in muscle development in mice. Multiple transcript variants encoding different isoforms have been found for this gene.

Full Name

SRSF Protein Kinase 3

Function

Serine/arginine-rich protein-specific kinase which specifically phosphorylates its substrates at serine residues located in regions rich in arginine/serine dipeptides, known as RS domains. Phosphorylates the SR splicing factor SRSF1 and the lamin-B receptor (LBR) in vitro. Required for normal muscle development (By similarity).

Biological Process

Biological Process cell differentiationIEA:UniProtKB-KW
Biological Process intracellular signal transductionManual Assertion Based On ExperimentIBA:GO_Central
Biological Process muscle tissue developmentISS:UniProtKB
Biological Process protein phosphorylationIEA:Ensembl
Biological Process regulation of mRNA processingManual Assertion Based On ExperimentIBA:GO_Central
Biological Process skeletal muscle tissue developmentIEA:Ensembl
Biological Process spliceosomal complex assemblyManual Assertion Based On ExperimentIBA:GO_Central

Cellular Location

cytoplasm
nucleus

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Anti-SRPK3 antibodies

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Mouse Anti-SRPK3 Recombinant Antibody (CBXS-1906) (CBMAB-S4696-CQ)

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Target: SRPK3

Host: Mouse

Antibody Isotype: IgG2b

Specificity: Human

Clone: CBXS-1906

Application*: WB

Mouse Anti-SRPK3 Recombinant Antibody (CBXS-1905) (CBMAB-S4695-CQ)

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Target: SRPK3

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: CBXS-1905

Application*: WB, IH

Mouse Anti-SRPK3 Recombinant Antibody (CBXS-5227) (CBMAB-S2443-CQ)

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Target: SRPK3

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: CBXS-5227

Application*: WB

Human Recombinant SRPK3 protein, GST Tag (V2LY-0526-LY6948)

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Target: SRPK3

Expressed Host: Baculovirus-Insect Cells

Sequence: Amino Acid: 1-566

Tag: GST Tag

Human Recombinant SRPK3, Active protein, GST Tag (V2LY-0526-LY6947)

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Target: SRPK3

Expressed Host: Baculovirus-Insect Cells

Sequence: Amino Acid: Full Length

Tag: GST Tag

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Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized)

Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)

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(P): Predicted

* Abbreviations

AActivation
AGAgonist
APApoptosis
BBlocking
BABioassay
BIBioimaging
CImmunohistochemistry-Frozen Sections
CIChromatin Immunoprecipitation
CTCytotoxicity
CSCostimulation
DDepletion
DBDot Blot

EELISA
ECELISA(Cap)
EDELISA(Det)
ESELISpot
EMElectron Microscopy
FFlow Cytometry
FNFunction Assay
GSGel Supershift
IInhibition
IAEnzyme Immunoassay
ICImmunocytochemistry
IDImmunodiffusion
IEImmunoelectrophoresis

IFImmunofluorescence
IGImmunochromatography
IHImmunohistochemistry
IMImmunomicroscopy
IOImmunoassay
IPImmunoprecipitation
ISIntracellular Staining for Flow Cytometry
LALuminex Assay
LFLateral Flow Immunoassay
MMicroarray
MCMass Cytometry/CyTOF
MDMeDIP

MSElectrophoretic Mobility Shift Assay
NNeutralization
PImmunohistologyp-Paraffin Sections
PAPeptide Array
PEPeptide ELISA
PLProximity Ligation Assay
RRadioimmunoassay
SStimulation
SESandwich ELISA
SHIn situ hybridization
TCTissue Culture
WBWestern Blot

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