SRPK3
This gene encodes a protein kinase similar to a protein kinase which is specific for the SR (serine/arginine-rich domain) family of splicing factors. A highly similar protein has been shown to play a role in muscle development in mice. Multiple transcript variants encoding different isoforms have been found for this gene.
Full Name
SRSF Protein Kinase 3
Function
Serine/arginine-rich protein-specific kinase which specifically phosphorylates its substrates at serine residues located in regions rich in arginine/serine dipeptides, known as RS domains. Phosphorylates the SR splicing factor SRSF1 and the lamin-B receptor (LBR) in vitro. Required for normal muscle development (By similarity).
Biological Process
Biological Process cell differentiationIEA:UniProtKB-KW
Biological Process intracellular signal transductionManual Assertion Based On ExperimentIBA:GO_Central
Biological Process muscle tissue developmentISS:UniProtKB
Biological Process protein phosphorylationIEA:Ensembl
Biological Process regulation of mRNA processingManual Assertion Based On ExperimentIBA:GO_Central
Biological Process skeletal muscle tissue developmentIEA:Ensembl
Biological Process spliceosomal complex assemblyManual Assertion Based On ExperimentIBA:GO_Central
Biological Process intracellular signal transductionManual Assertion Based On ExperimentIBA:GO_Central
Biological Process muscle tissue developmentISS:UniProtKB
Biological Process protein phosphorylationIEA:Ensembl
Biological Process regulation of mRNA processingManual Assertion Based On ExperimentIBA:GO_Central
Biological Process skeletal muscle tissue developmentIEA:Ensembl
Biological Process spliceosomal complex assemblyManual Assertion Based On ExperimentIBA:GO_Central
Cellular Location
cytoplasm
nucleus
nucleus
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Anti-SRPK3 antibodies
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Target: SRPK3
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: CBXS-1906
Application*: WB
Target: SRPK3
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBXS-1905
Application*: WB, IH
Target: SRPK3
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBXS-5227
Application*: WB
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For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
- AActivation
- AGAgonist
- APApoptosis
- BBlocking
- BABioassay
- BIBioimaging
- CImmunohistochemistry-Frozen Sections
- CIChromatin Immunoprecipitation
- CTCytotoxicity
- CSCostimulation
- DDepletion
- DBDot Blot
- EELISA
- ECELISA(Cap)
- EDELISA(Det)
- ESELISpot
- EMElectron Microscopy
- FFlow Cytometry
- FNFunction Assay
- GSGel Supershift
- IInhibition
- IAEnzyme Immunoassay
- ICImmunocytochemistry
- IDImmunodiffusion
- IEImmunoelectrophoresis
- IFImmunofluorescence
- IHImmunohistochemistry
- IMImmunomicroscopy
- IOImmunoassay
- IPImmunoprecipitation
- ISIntracellular Staining for Flow Cytometry
- LALuminex Assay
- LFLateral Flow Immunoassay
- MMicroarray
- MCMass Cytometry/CyTOF
- MDMeDIP
- MSElectrophoretic Mobility Shift Assay
- NNeutralization
- PImmunohistologyp-Paraffin Sections
- PAPeptide Array
- PEPeptide ELISA
- PLProximity Ligation Assay
- RRadioimmunoassay
- SStimulation
- SESandwich ELISA
- SHIn situ hybridization
- TCTissue Culture
- WBWestern Blot

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