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Mouse Anti-SRPK3 Recombinant Antibody (CBXS-5227) (CBMAB-S2443-CQ)

This product is a mouse antibody that recognizes SRPK3. The antibody CBXS-5227 can be used for immunoassay techniques such as: WB.
See all SRPK3 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
CBXS-5227
Antibody Isotype
IgG1
Application
WB

Basic Information

Immunogen
Human recombinant protein fragment corresponding to amino acids 245-330 of human SRPK3 (NP_055185)
Specificity
Human
Antibody Isotype
IgG1
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS, pH 7.3, 1% BSA, 50% glycerol
Preservative
0.02% sodium azide
Concentration
1 mg/mL
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
SRSF Protein Kinase 3
Introduction
This gene encodes a protein kinase similar to a protein kinase which is specific for the SR (serine/arginine-rich domain) family of splicing factors. A highly similar protein has been shown to play a role in muscle development in mice. Multiple transcript variants encoding different isoforms have been found for this gene.
Entrez Gene ID
UniProt ID
Alternative Names
SRSF Protein Kinase 3; Serine/Threonine-Protein Kinase 23; Muscle-Specific Serine Kinase 1; SR-Protein-Specific Kinase 3; Serine/Threonine Kinase 23; SFRS Protein Kinase 3; EC 2.7.11.1;
Function
Serine/arginine-rich protein-specific kinase which specifically phosphorylates its substrates at serine residues located in regions rich in arginine/serine dipeptides, known as RS domains. Phosphorylates the SR splicing factor SRSF1 and the lamin-B receptor (LBR) in vitro. Required for normal muscle development (By similarity).
Biological Process
Biological Process cell differentiationIEA:UniProtKB-KW
Biological Process intracellular signal transductionManual Assertion Based On ExperimentIBA:GO_Central
Biological Process muscle tissue developmentISS:UniProtKB
Biological Process protein phosphorylationIEA:Ensembl
Biological Process regulation of mRNA processingManual Assertion Based On ExperimentIBA:GO_Central
Biological Process skeletal muscle tissue developmentIEA:Ensembl
Biological Process spliceosomal complex assemblyManual Assertion Based On ExperimentIBA:GO_Central
Cellular Location
cytoplasm
nucleus
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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