Mouse Anti-SRPK3 Recombinant Antibody (CBXS-5227) (CBMAB-S2443-CQ)

Name: Mouse Anti-SRPK3 Recombinant Antibody (CBXS-5227)
SKU: CBMAB-S2443-CQ
Rating: 5 (1 reviews)

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Datasheet

SDS

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Basic Information

Host Animal

Mouse

Clone

CBXS-5227

Application

Immunogen

Human recombinant protein fragment corresponding to amino acids 245-330 of human SRPK3 (NP_055185)

Specificity

Human

Antibody Isotype

IgG1

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Liquid

Buffer

PBS, pH 7.3, 1% BSA, 50% glycerol

Preservative

0.02% sodium azide

Concentration

1 mg/mL

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

More Infomation

Target

Full Name

SRSF Protein Kinase 3

Introduction

This gene encodes a protein kinase similar to a protein kinase which is specific for the SR (serine/arginine-rich domain) family of splicing factors. A highly similar protein has been shown to play a role in muscle development in mice. Multiple transcript variants encoding different isoforms have been found for this gene.

Entrez Gene ID

26576

UniProt ID

Q9UPE1

Alternative Names

SRSF Protein Kinase 3; Serine/Threonine-Protein Kinase 23; Muscle-Specific Serine Kinase 1; SR-Protein-Specific Kinase 3; Serine/Threonine Kinase 23; SFRS Protein Kinase 3; EC 2.7.11.1;

Function

Serine/arginine-rich protein-specific kinase which specifically phosphorylates its substrates at serine residues located in regions rich in arginine/serine dipeptides, known as RS domains. Phosphorylates the SR splicing factor SRSF1 and the lamin-B receptor (LBR) in vitro. Required for normal muscle development (By similarity).

Biological Process

Biological Process cell differentiationIEA:UniProtKB-KW
Biological Process intracellular signal transductionManual Assertion Based On ExperimentIBA:GO_Central
Biological Process muscle tissue developmentISS:UniProtKB
Biological Process protein phosphorylationIEA:Ensembl
Biological Process regulation of mRNA processingManual Assertion Based On ExperimentIBA:GO_Central
Biological Process skeletal muscle tissue developmentIEA:Ensembl
Biological Process spliceosomal complex assemblyManual Assertion Based On ExperimentIBA:GO_Central

Cellular Location

cytoplasm
nucleus

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme-Linked Immunospot (ELISpot)
Proteogenomics
Other Protocols

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Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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