STK16

STK16 (Serine/Threonine Kinase 16) is a Protein Coding gene. Diseases associated with STK16 include Amyotrophic Lateral Sclerosis 22 With Or Without Frontotemporal Dementia and Diffuse Mesangial Sclerosis. Among its related pathways are Sweet Taste Signaling. Gene Ontology (GO) annotations related to this gene include transferase activity, transferring phosphorus-containing groups and protein tyrosine kinase activity.Membrane-associated protein kinase that phosphorylates on serine and threonine residues. In vitro substrates include DRG1, ENO1 and EIF4EBP1. Also autophosphorylates. May be involved in secretory vesicle trafficking or intracellular signaling. May have a role in regulating stromal-epithelial interactions that occur during ductal morphogenesis in the mammary gland. May be involved in TGF-beta signaling. Able to autophosphorylate on Tyr residue; it is however unclear whether it has tyrosine-protein kinase toward other proteins.
Full Name
STK16
Function
Membrane-associated protein kinase that phosphorylates on serine and threonine residues. In vitro substrates include DRG1, ENO1 and EIF4EBP1. Also autophosphorylates. May be involved in secretory vesicle trafficking or intracellular signaling. May have a role in regulating stromal-epithelial interactions that occur during ductal morphogenesis in the mammary gland. May be involved in TGF-beta signaling. Able to autophosphorylate on Tyr residue; it is however unclear whether it has tyrosine-protein kinase toward other proteins.
Biological Process
Biological Process cellular response to transforming growth factor beta stimulusIEA:Ensembl
Biological Process positive regulation of transcription by RNA polymerase IIIEA:Ensembl
Biological Process protein autophosphorylationManual Assertion Based On ExperimentIDA:UniProtKB
Cellular Location
Cytoplasm, perinuclear region
Membrane
Associates with Golgi and Golgi-derived vesicles.
PTM
Mainly autophosphorylated on serine/threonine residues. Also autophosphorylated on Tyr-198.
It is uncertain whether palmitoylation is on Cys-6 and/or Cys-8.
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Anti-STK16 antibodies

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Mouse Anti-STK16 Recombinant Antibody (M2) (CBMAB-A8698-LY)

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Target: STK16
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: M2
Application*: WB, E
Datasheet SDS

Mouse Anti-STK16 Recombinant Antibody (2G6) (CBMAB-A8697-LY)

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Target: STK16
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: 2G6
Application*: WB, E
Datasheet SDS

STK16 Matched Antibody Pair (1157) (APMAB-1157LY)

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Target: STK16
Specificity: Human
Datasheet SDS

STK16 Matched Antibody Pair (1156) (APMAB-1156LY)

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Target: STK16
Specificity: Human
Datasheet SDS

Mouse Anti-STK16 Recombinant Antibody (CBXS-0781) (CBMAB-S3708-CQ)

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Target: STK16
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CBXS-0781
Application*: E, WB, P
Datasheet SDS

Mouse Anti-STK16 Recombinant Antibody (CBXS-0780) (CBMAB-S3707-CQ)

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Target: STK16
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CBXS-0780
Application*: SE, IR, E, WB, P
Datasheet SDS

Mouse Anti-STK16 Recombinant Antibody (CBXS-6120) (CBMAB-S2955-CQ)

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Target: STK16
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBXS-6120
Application*: E, WB
Datasheet SDS

Mouse Anti-STK16 Recombinant Antibody (CBXS-5504) (CBMAB-S2713-CQ)

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Target: STK16
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CBXS-5504
Application*: E, P, IR, WB
Datasheet SDS

Mouse Anti-STK16 Recombinant Antibody (CBXS-5661) (CBMAB-S0261-CQ)

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Target: STK16
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CBXS-5661
Application*: WB, E
Datasheet SDS
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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IGImmunochromatography
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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