Human Recombinant STK16 protein, GST Tag (V2LY-0526-LY6987)

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Basic Information

Expressed Host
Baculovirus-Insect Cells
Protein Species
Human
Tag
GST Tag
Protein Construction
This product is Human Recombinant STK16 protein, GST Tag consist of Amino Acid: Full Length and predicts a molecular mass of 58 kDa.
Molecule Mass
58 kDa
Sequence
Amino Acid: Full Length
Species
Human

Formulations & Storage [For reference only, actual COA shall prevail!]

Purity
Batch dependent.
Endotoxin
Please contact us for more information.
Format
Liquid
Buffer
PBS
Preservative
None
Storage
Store product at -70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
More Infomation

Target

Full Name
STK16
Function
Membrane-associated protein kinase that phosphorylates on serine and threonine residues. In vitro substrates include DRG1, ENO1 and EIF4EBP1. Also autophosphorylates. May be involved in secretory vesicle trafficking or intracellular signaling. May have a role in regulating stromal-epithelial interactions that occur during ductal morphogenesis in the mammary gland. May be involved in TGF-beta signaling. Able to autophosphorylate on Tyr residue; it is however unclear whether it has tyrosine-protein kinase toward other proteins.
Biological Process
Biological Process cellular response to transforming growth factor beta stimulusIEA:Ensembl
Biological Process positive regulation of transcription by RNA polymerase IIIEA:Ensembl
Biological Process protein autophosphorylationManual Assertion Based On ExperimentIDA:UniProtKB
Cellular Location
Cytoplasm, perinuclear region
Membrane
Associates with Golgi and Golgi-derived vesicles.
PTM
Mainly autophosphorylated on serine/threonine residues. Also autophosphorylated on Tyr-198.
It is uncertain whether palmitoylation is on Cys-6 and/or Cys-8.
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For research use only. Not intended for any clinical use.

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