Mouse Anti-STK16 Recombinant Antibody (CBXS-5661) (CBMAB-S0261-CQ)

Name: Mouse Anti-STK16 Recombinant Antibody (CBXS-5661)
SKU: CBMAB-S0261-CQ
Rating: 5 (1 reviews)

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Datasheet

SDS

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Basic Information

Host Animal

Mouse

Clone

CBXS-5661

Application

WB, ELISA

Immunogen

Recombinant human STK16 (1-305aa) purified from E. coli

Specificity

Human

Antibody Isotype

IgG1, κ

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Concentration

1 mg/mL

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

More Infomation

Target

Full Name

STK16

Introduction

STK16 (Serine/Threonine Kinase 16) is a Protein Coding gene. Diseases associated with STK16 include Amyotrophic Lateral Sclerosis 22 With Or Without Frontotemporal Dementia and Diffuse Mesangial Sclerosis. Among its related pathways are Sweet Taste Signaling. Gene Ontology (GO) annotations related to this gene include transferase activity, transferring phosphorus-containing groups and protein tyrosine kinase activity.Membrane-associated protein kinase that phosphorylates on serine and threonine residues. In vitro substrates include DRG1, ENO1 and EIF4EBP1. Also autophosphorylates. May be involved in secretory vesicle trafficking or intracellular signaling. May have a role in regulating stromal-epithelial interactions that occur during ductal morphogenesis in the mammary gland. May be involved in TGF-beta signaling. Able to autophosphorylate on Tyr residue; it is however unclear whether it has tyrosine-protein kinase toward other proteins.

Entrez Gene ID

8576

UniProt ID

O75716

Alternative Names

KRCT; MPSK; PKL12; PSK; TSF1; hPSK

Function

Membrane-associated protein kinase that phosphorylates on serine and threonine residues. In vitro substrates include DRG1, ENO1 and EIF4EBP1. Also autophosphorylates. May be involved in secretory vesicle trafficking or intracellular signaling. May have a role in regulating stromal-epithelial interactions that occur during ductal morphogenesis in the mammary gland. May be involved in TGF-beta signaling. Able to autophosphorylate on Tyr residue; it is however unclear whether it has tyrosine-protein kinase toward other proteins.

Biological Process

Biological Process cellular response to transforming growth factor beta stimulusIEA:Ensembl
Biological Process positive regulation of transcription by RNA polymerase IIIEA:Ensembl
Biological Process protein autophosphorylationManual Assertion Based On ExperimentIDA:UniProtKB

Cellular Location

Cytoplasm, perinuclear region
Membrane
Associates with Golgi and Golgi-derived vesicles.

PTM

Mainly autophosphorylated on serine/threonine residues. Also autophosphorylated on Tyr-198.
It is uncertain whether palmitoylation is on Cys-6 and/or Cys-8.

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme-Linked Immunospot (ELISpot)
Proteogenomics
Other Protocols

Antibody Pairs

STK16 Matched Antibody Pair (1156) (CAT#: APMAB-1156LY)

STK16 Matched Antibody Pair (1157) (CAT#: APMAB-1157LY)

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STK16 Matched Antibody Pair (1157) (CAT#: APMAB-1157LY)

STK16 Matched Antibody Pair (1156) (CAT#: APMAB-1156LY)

Mouse Anti-STK16 Recombinant Antibody (CBXS-0781) (CAT#: CBMAB-S3708-CQ)

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Mouse Anti-STK16 Recombinant Antibody (CBXS-0780) (CAT#: CBMAB-S3707-CQ)

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Mouse Anti-STK16 Recombinant Antibody (CBXS-6120) (CAT#: CBMAB-S2955-CQ)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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