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Mouse Anti-STK16 Recombinant Antibody (M2) (CBMAB-A8698-LY)


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Summary

Host Animal
Mouse
Specificity
Human
Clone
M2
Antibody Isotype
IgG2a, κ
Application
WB, ELISA

Basic Information

Immunogen
STK16 (NP_001008910, 1 a.a. ~ 100 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Specificity
Human
Antibody Isotype
IgG2a, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Purity
> 95% Purity determined by SDS-PAGE.
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
STK16
Entrez Gene ID
8576
UniProt ID
O75716
Alternative Names
FLJ39635; KRCT; MPSK; PKL12; TSF1
Function
Membrane-associated protein kinase that phosphorylates on serine and threonine residues. In vitro substrates include DRG1, ENO1 and EIF4EBP1. Also autophosphorylates. May be involved in secretory vesicle trafficking or intracellular signaling. May have a role in regulating stromal-epithelial interactions that occur during ductal morphogenesis in the mammary gland. May be involved in TGF-beta signaling. Able to autophosphorylate on Tyr residue; it is however unclear whether it has tyrosine-protein kinase toward other proteins.
Biological Process
Biological Process cellular response to transforming growth factor beta stimulusIEA:Ensembl
Biological Process positive regulation of transcription by RNA polymerase IIIEA:Ensembl
Biological Process protein autophosphorylationManual Assertion Based On ExperimentIDA:UniProtKB
Cellular Location
Cytoplasm, perinuclear region
Membrane
Associates with Golgi and Golgi-derived vesicles.
PTM
Mainly autophosphorylated on serine/threonine residues. Also autophosphorylated on Tyr-198.
It is uncertain whether palmitoylation is on Cys-6 and/or Cys-8.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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