SUGCT

This gene encodes a protein that is similar to members of the CaiB/baiF CoA-transferase protein family. Mutations in this gene are associated with glutaric aciduria type III. Alternate splicing results in multiple transcript variants.

Full Name

Succinyl-CoA:Glutarate-CoA Transferase

Function

Catalyzes the succinyl-CoA-dependent conversion of glutarate to glutaryl-CoA. Can use different dicarboxylic acids as CoA acceptors, the preferred ones are glutarate, succinate, adipate, and 3-hydroxymethylglutarate.

Cellular Location

Mitochondrion

Involvement in disease

Glutaric aciduria 3 (GA3):
A metabolic disorder due to peroxisomal glutaryl-CoA oxidase deficiency and characterized by the excretion of abnormal quantities of glutaric acid but low 3-hydroxyglutaric acid.

Anti-SUGCT antibodies

Mouse Anti-SUGCT (AA 335-435) Recombinant Antibody (CBXS-0839) (CBMAB-S3763-CQ)

Datasheet

SDS

Target: SUGCT

Host: Mouse

Antibody Isotype: IgG2a, κ

Specificity: Human

Clone: CBXS-0839

Application*: E

Mouse Anti-SUGCT Recombinant Antibody (CBXS-4374) (CBMAB-S1617-CQ)

Datasheet

SDS

Target: SUGCT

Host: Mouse

Antibody Isotype: IgG2a, κ

Specificity: Human

Clone: CBXS-4374

Application*: E

Mouse Anti-SUGCT (AA 335-434) Recombinant Antibody (CBFYC-3142) (CBMAB-C3219-FY)

Datasheet

SDS

Target: SUGCT

Host: Mouse

Antibody Isotype: IgG2a, κ

Specificity: Human

Clone: CBFYC-3142

Application*: E

Mouse Anti-SUGCT Recombinant Antibody (2B11) (CBMAB-A0993-LY)

Datasheet

SDS

Target: SUGCT

Host: Mouse

Antibody Isotype: IgG2a, κ

Specificity: Human

Clone: 2B11

Application*: SE, E

For Research Use Only. Not For Clinical Use.

(P): Predicted

* Abbreviations

IFImmunofluorescence

IHImmunohistochemistry

IPImmunoprecipitation

WBWestern Blot

EELISA

MMicroarray

CIChromatin Immunoprecipitation

FFlow Cytometry

FNFunction Assay

IDImmunodiffusion

RRadioimmunoassay

TCTissue Culture

GSGel Supershift

NNeutralization

BBlocking

AActivation

IInhibition

DDepletion

ESELISpot

DBDot Blot

MCMass Cytometry/CyTOF

CTCytotoxicity

SStimulation

AGAgonist

APApoptosis

IMImmunomicroscopy

BABioassay

CSCostimulation

EMElectron Microscopy

IEImmunoelectrophoresis

PAPeptide Array

ICImmunocytochemistry

PEPeptide ELISA

MDMeDIP

SHIn situ hybridization

IAEnzyme Immunoassay

SEsandwich ELISA

PLProximity Ligation Assay

ECELISA(Cap)

EDELISA(Det)

BIBioimaging

IOImmunoassay

LFLateral Flow Immunoassay

LALuminex Assay

CImmunohistochemistry-Frozen Sections

PImmunohistologyp-Paraffin Sections

ISIntracellular Staining for Flow Cytometry

MSElectrophoretic Mobility Shift Assay

RIRNA Binding Protein Immunoprecipitation (RIP)