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SUGCT

This gene encodes a protein that is similar to members of the CaiB/baiF CoA-transferase protein family. Mutations in this gene are associated with glutaric aciduria type III. Alternate splicing results in multiple transcript variants.

Full Name

Succinyl-CoA:Glutarate-CoA Transferase

Function

Catalyzes the succinyl-CoA-dependent conversion of glutarate to glutaryl-CoA. Can use different dicarboxylic acids as CoA acceptors, the preferred ones are glutarate, succinate, adipate, and 3-hydroxymethylglutarate.

Cellular Location

Mitochondrion

Involvement in disease

Glutaric aciduria 3 (GA3):
A metabolic disorder due to peroxisomal glutaryl-CoA oxidase deficiency and characterized by the excretion of abnormal quantities of glutaric acid but low 3-hydroxyglutaric acid.

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Anti-SUGCT antibodies

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Mouse Anti-SUGCT (AA 335-435) Recombinant Antibody (CBXS-0839) (CBMAB-S3763-CQ)

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Target: SUGCT

Host: Mouse

Antibody Isotype: IgG2a, κ

Specificity: Human

Clone: CBXS-0839

Application*: E

Mouse Anti-SUGCT Recombinant Antibody (CBXS-4374) (CBMAB-S1617-CQ)

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Target: SUGCT

Host: Mouse

Antibody Isotype: IgG2a, κ

Specificity: Human

Clone: CBXS-4374

Application*: E

Mouse Anti-SUGCT (AA 335-434) Recombinant Antibody (CBFYC-3142) (CBMAB-C3219-FY)

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Target: SUGCT

Host: Mouse

Antibody Isotype: IgG2a, κ

Specificity: Human

Clone: CBFYC-3142

Application*: E

Mouse Anti-SUGCT Recombinant Antibody (2B11) (CBMAB-A0993-LY)

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Target: SUGCT

Host: Mouse

Antibody Isotype: IgG2a, κ

Specificity: Human

Clone: 2B11

Application*: SE, E

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(P): Predicted

* Abbreviations

AActivation
AGAgonist
APApoptosis
BBlocking
BABioassay
BIBioimaging
CImmunohistochemistry-Frozen Sections
CIChromatin Immunoprecipitation
CTCytotoxicity
CSCostimulation
DDepletion
DBDot Blot

EELISA
ECELISA(Cap)
EDELISA(Det)
ESELISpot
EMElectron Microscopy
FFlow Cytometry
FNFunction Assay
GSGel Supershift
IInhibition
IAEnzyme Immunoassay
ICImmunocytochemistry
IDImmunodiffusion
IEImmunoelectrophoresis

IFImmunofluorescence
IGImmunochromatography
IHImmunohistochemistry
IMImmunomicroscopy
IOImmunoassay
IPImmunoprecipitation
ISIntracellular Staining for Flow Cytometry
LALuminex Assay
LFLateral Flow Immunoassay
MMicroarray
MCMass Cytometry/CyTOF
MDMeDIP

MSElectrophoretic Mobility Shift Assay
NNeutralization
PImmunohistologyp-Paraffin Sections
PAPeptide Array
PEPeptide ELISA
PLProximity Ligation Assay
RRadioimmunoassay
SStimulation
SESandwich ELISA
SHIn situ hybridization
TCTissue Culture
WBWestern Blot

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