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SYNGR3

This gene encodes an integral membrane protein. The exact function of this protein is unclear, but studies of a similar murine protein suggest that it is a synaptic vesicle protein that also interacts with the dopamine transporter. The gene product belongs to the synaptogyrin gene family.

Full Name

Synaptogyrin 3

Function

May play a role in regulated exocytosis. May indirectly regulate the activity of the plasma membrane dopamine transporter SLC6A3 and thereby regulate dopamine transport back from the synaptic cleft into the presynaptic terminal.

Biological Process

Biological Process neurotransmitter uptakeIEA:Ensembl
Biological Process positive regulation of transporter activityISS:UniProtKB
Biological Process regulated exocytosisISS:UniProtKB
Biological Process substantia nigra developmentHEP:UniProtKB1 Publication

Cellular Location

Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane
Synapse
Found at the neuromuscular synapses.

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Anti-SYNGR3 antibodies

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Mouse Anti-SYNGR3 Recombinant Antibody (CBXS-2263) (CBMAB-S5025-CQ)

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Target: SYNGR3

Host: Mouse

Specificity: Mouse, Rat, Human

Clone: CBXS-2263

Application*: WB, IP, IF, E

Mouse Anti-SYNGR3 Recombinant Antibody (CBXS-2247) (CBMAB-S5009-CQ)

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Target: SYNGR3

Host: Mouse

Specificity: Mouse, Rat, Human

Clone: CBXS-2247

Application*: WB, IP, IF, E

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(P): Predicted

* Abbreviations

AActivation
AGAgonist
APApoptosis
BBlocking
BABioassay
BIBioimaging
CImmunohistochemistry-Frozen Sections
CIChromatin Immunoprecipitation
CTCytotoxicity
CSCostimulation
DDepletion
DBDot Blot

EELISA
ECELISA(Cap)
EDELISA(Det)
ESELISpot
EMElectron Microscopy
FFlow Cytometry
FNFunction Assay
GSGel Supershift
IInhibition
IAEnzyme Immunoassay
ICImmunocytochemistry
IDImmunodiffusion
IEImmunoelectrophoresis

IFImmunofluorescence
IGImmunochromatography
IHImmunohistochemistry
IMImmunomicroscopy
IOImmunoassay
IPImmunoprecipitation
ISIntracellular Staining for Flow Cytometry
LALuminex Assay
LFLateral Flow Immunoassay
MMicroarray
MCMass Cytometry/CyTOF
MDMeDIP

MSElectrophoretic Mobility Shift Assay
NNeutralization
PImmunohistologyp-Paraffin Sections
PAPeptide Array
PEPeptide ELISA
PLProximity Ligation Assay
RRadioimmunoassay
SStimulation
SESandwich ELISA
SHIn situ hybridization
TCTissue Culture
WBWestern Blot

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