SYNGR3
This gene encodes an integral membrane protein. The exact function of this protein is unclear, but studies of a similar murine protein suggest that it is a synaptic vesicle protein that also interacts with the dopamine transporter. The gene product belongs to the synaptogyrin gene family.
Full Name
Synaptogyrin 3
Function
May play a role in regulated exocytosis. May indirectly regulate the activity of the plasma membrane dopamine transporter SLC6A3 and thereby regulate dopamine transport back from the synaptic cleft into the presynaptic terminal.
Biological Process
Biological Process neurotransmitter uptakeIEA:Ensembl
Biological Process positive regulation of transporter activityISS:UniProtKB
Biological Process regulated exocytosisISS:UniProtKB
Biological Process substantia nigra developmentHEP:UniProtKB1 Publication
Biological Process positive regulation of transporter activityISS:UniProtKB
Biological Process regulated exocytosisISS:UniProtKB
Biological Process substantia nigra developmentHEP:UniProtKB1 Publication
Cellular Location
Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane
Synapse
Found at the neuromuscular synapses.
Synapse
Found at the neuromuscular synapses.
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Anti-SYNGR3 antibodies
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Target: SYNGR3
Host: Mouse
Specificity: Mouse, Rat, Human
Clone: CBXS-2263
Application*: WB, IP, IF, E
Target: SYNGR3
Host: Mouse
Specificity: Mouse, Rat, Human
Clone: CBXS-2247
Application*: WB, IP, IF, E
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For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
- AActivation
- AGAgonist
- APApoptosis
- BBlocking
- BABioassay
- BIBioimaging
- CImmunohistochemistry-Frozen Sections
- CIChromatin Immunoprecipitation
- CTCytotoxicity
- CSCostimulation
- DDepletion
- DBDot Blot
- EELISA
- ECELISA(Cap)
- EDELISA(Det)
- ESELISpot
- EMElectron Microscopy
- FFlow Cytometry
- FNFunction Assay
- GSGel Supershift
- IInhibition
- IAEnzyme Immunoassay
- ICImmunocytochemistry
- IDImmunodiffusion
- IEImmunoelectrophoresis
- IFImmunofluorescence
- IGImmunochromatography
- IHImmunohistochemistry
- IMImmunomicroscopy
- IOImmunoassay
- IPImmunoprecipitation
- ISIntracellular Staining for Flow Cytometry
- LALuminex Assay
- LFLateral Flow Immunoassay
- MMicroarray
- MCMass Cytometry/CyTOF
- MDMeDIP
- MSElectrophoretic Mobility Shift Assay
- NNeutralization
- PImmunohistologyp-Paraffin Sections
- PAPeptide Array
- PEPeptide ELISA
- PLProximity Ligation Assay
- RRadioimmunoassay
- SStimulation
- SESandwich ELISA
- SHIn situ hybridization
- TCTissue Culture
- WBWestern Blot
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