TECRL

TECRL contains a ubiquitin-like domain in the N-terminal region, three transmembrane segments and a C-terminal 3-oxo-5-alpha steroid 4-dehydrogenase domain. It belongs to the steroid 5-alpha reductase family. Mutations in TECRL result in ventricular tachycardia, catecholaminergic polymorphic, 3.
Full Name
Trans-2, 3-Enoyl-CoA Reductase Like
Biological Process
Very long-chain fatty acid biosynthetic process
Cellular Location
Membrane
Endoplasmic reticulum
Involvement in disease
Ventricular tachycardia, catecholaminergic polymorphic, 3 (CPVT3):
An arrhythmogenic disorder characterized by stress-induced, bidirectional ventricular tachycardia that may degenerate into cardiac arrest and cause sudden death. Patients present with recurrent syncope, or sudden death after physical activity or emotional stress. CPVT3 is an autosomal recessive disorder with onset at early age and associated with sudden death in childhood. Patients manifest QT prolongation on adrenergic stimulation.
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Anti-TECRL antibodies

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Mouse Anti-TECRL Recombinant Antibody (CBYJT-2496) (CBMAB-T1645-YJ)

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Target: TECRL
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYJT-2496
Application*: WB
Datasheet SDS

Mouse Anti-TECRL Recombinant Antibody (CBYJT-2495) (CBMAB-T1644-YJ)

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Target: TECRL
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYJT-2495
Application*: WB
Datasheet SDS
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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IGImmunochromatography
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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