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TECRL

TECRL contains a ubiquitin-like domain in the N-terminal region, three transmembrane segments and a C-terminal 3-oxo-5-alpha steroid 4-dehydrogenase domain. It belongs to the steroid 5-alpha reductase family. Mutations in TECRL result in ventricular tachycardia, catecholaminergic polymorphic, 3.

Full Name

Trans-2, 3-Enoyl-CoA Reductase Like

Biological Process

Very long-chain fatty acid biosynthetic process

Cellular Location

Membrane
Endoplasmic reticulum

Involvement in disease

Ventricular tachycardia, catecholaminergic polymorphic, 3 (CPVT3):
An arrhythmogenic disorder characterized by stress-induced, bidirectional ventricular tachycardia that may degenerate into cardiac arrest and cause sudden death. Patients present with recurrent syncope, or sudden death after physical activity or emotional stress. CPVT3 is an autosomal recessive disorder with onset at early age and associated with sudden death in childhood. Patients manifest QT prolongation on adrenergic stimulation.

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Anti-TECRL antibodies

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Mouse Anti-TECRL Recombinant Antibody (CBYJT-2496) (CBMAB-T1645-YJ)

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Target: TECRL

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: CBYJT-2496

Application*: WB

Mouse Anti-TECRL Recombinant Antibody (CBYJT-2495) (CBMAB-T1644-YJ)

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Target: TECRL

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: CBYJT-2495

Application*: WB

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(P): Predicted

* Abbreviations

AActivation
AGAgonist
APApoptosis
BBlocking
BABioassay
BIBioimaging
CImmunohistochemistry-Frozen Sections
CIChromatin Immunoprecipitation
CTCytotoxicity
CSCostimulation
DDepletion
DBDot Blot

EELISA
ECELISA(Cap)
EDELISA(Det)
ESELISpot
EMElectron Microscopy
FFlow Cytometry
FNFunction Assay
GSGel Supershift
IInhibition
IAEnzyme Immunoassay
ICImmunocytochemistry
IDImmunodiffusion
IEImmunoelectrophoresis

IFImmunofluorescence
IGImmunochromatography
IHImmunohistochemistry
IMImmunomicroscopy
IOImmunoassay
IPImmunoprecipitation
ISIntracellular Staining for Flow Cytometry
LALuminex Assay
LFLateral Flow Immunoassay
MMicroarray
MCMass Cytometry/CyTOF
MDMeDIP

MSElectrophoretic Mobility Shift Assay
NNeutralization
PImmunohistologyp-Paraffin Sections
PAPeptide Array
PEPeptide ELISA
PLProximity Ligation Assay
RRadioimmunoassay
SStimulation
SESandwich ELISA
SHIn situ hybridization
TCTissue Culture
WBWestern Blot

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