Mouse Anti-TECRL Recombinant Antibody (CBYJT-2495) (CBMAB-T1644-YJ)

Name: Mouse Anti-TECRL Recombinant Antibody (CBYJT-2495)
SKU: CBMAB-T1644-YJ
Rating: 5 (1 reviews)

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Datasheet

SDS

Request for COA

Datasheet Target Q & As Review & reward Protocols Associated Products

Basic Information

Host Animal

Mouse

Clone

CBYJT-2495

Application

Immunogen

This SRD5A2L2 antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 325-354 AA from the C-terminal region of human SRD5A2L2

Specificity

Human

Antibody Isotype

IgG1

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Buffer

PBS, pH 7.4

Storage

Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Epitope

aa 325-354

More Infomation

Target

Full Name

Trans-2, 3-Enoyl-CoA Reductase Like

Introduction

TECRL contains a ubiquitin-like domain in the N-terminal region, three transmembrane segments and a C-terminal 3-oxo-5-alpha steroid 4-dehydrogenase domain. It belongs to the steroid 5-alpha reductase family. Mutations in TECRL result in ventricular tachycardia, catecholaminergic polymorphic, 3.

Entrez Gene ID

253017

UniProt ID

Q5HYJ1

Alternative Names

Trans-2, 3-Enoyl-CoA Reductase Like; Steroid 5-Alpha-Reductase 2-Like 2 Protein; Glycoprotein, Synaptic 2-Like; SRD5A2L2; Steroid 5 Alpha-Reductase 2-Like 2; Trans-2, 3-Enoyl-CoA Reductase-Like

Biological Process

Very long-chain fatty acid biosynthetic process

Cellular Location

Membrane
Endoplasmic reticulum

Involvement in disease

Ventricular tachycardia, catecholaminergic polymorphic, 3 (CPVT3):
An arrhythmogenic disorder characterized by stress-induced, bidirectional ventricular tachycardia that may degenerate into cardiac arrest and cause sudden death. Patients present with recurrent syncope, or sudden death after physical activity or emotional stress. CPVT3 is an autosomal recessive disorder with onset at early age and associated with sudden death in childhood. Patients manifest QT prolongation on adrenergic stimulation.

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Related Products

Mouse Anti-TECRL Recombinant Antibody (CBYJT-2496) (CAT#: CBMAB-T1645-YJ)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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