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Mouse Anti-TECRL Recombinant Antibody (CBYJT-2496) (CBMAB-T1645-YJ)

Provided herein is a Mouse monoclonal antibody, which binds to TECRL (Trans-2, 3-Enoyl-CoA Reductase Like). The antibody can be used for immunoassay techniques, such as WB.
See all TECRL antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
CBYJT-2496
Antibody Isotype
IgG1
Application
WB

Basic Information

Specificity
Human
Antibody Isotype
IgG1
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Buffer
Ascites
Preservative
0.09% Sodium Azide
Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Epitope
aa 325-354

Target

Full Name
Trans-2, 3-Enoyl-CoA Reductase Like
Introduction
TECRL contains a ubiquitin-like domain in the N-terminal region, three transmembrane segments and a C-terminal 3-oxo-5-alpha steroid 4-dehydrogenase domain. It belongs to the steroid 5-alpha reductase family. Mutations in TECRL result in ventricular tachycardia, catecholaminergic polymorphic, 3.
Entrez Gene ID
253017
UniProt ID
Q5HYJ1
Alternative Names
Trans-2, 3-Enoyl-CoA Reductase Like; Steroid 5-Alpha-Reductase 2-Like 2 Protein; Glycoprotein, Synaptic 2-Like; SRD5A2L2; Steroid 5 Alpha-Reductase 2-Like 2; Trans-2, 3-Enoyl-CoA Reductase-Like
Biological Process
Very long-chain fatty acid biosynthetic process
Cellular Location
Membrane
Endoplasmic reticulum
Involvement in disease
Ventricular tachycardia, catecholaminergic polymorphic, 3 (CPVT3):
An arrhythmogenic disorder characterized by stress-induced, bidirectional ventricular tachycardia that may degenerate into cardiac arrest and cause sudden death. Patients present with recurrent syncope, or sudden death after physical activity or emotional stress. CPVT3 is an autosomal recessive disorder with onset at early age and associated with sudden death in childhood. Patients manifest QT prolongation on adrenergic stimulation.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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