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TES

Cancer-associated chromosomal changes often involve regions containing fragile sites. This gene maps to a commom fragile site on chromosome 7q31.2 designated FRA7G. This gene is similar to mouse Testin, a testosterone-responsive gene encoding a Sertoli cell secretory protein containing three LIM domains. LIM domains are double zinc-finger motifs that mediate protein-protein interactions between transcription factors, cytoskeletal proteins and signaling proteins. Multiple protein isoforms are encoded by transcript variants of this gene. [provided by RefSeq]

Full Name

testis derived transcript (3 LIM domains)

Function

Scaffold protein that may play a role in cell adhesion, cell spreading and in the reorganization of the actin cytoskeleton. Plays a role in the regulation of cell proliferation. May act as a tumor suppressor. Inhibits tumor cell growth.

Biological Process

Negative regulation of cell population proliferation

Cellular Location

Cytoplasm
Cell junction, focal adhesion
Detected along actin stress fibers.

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Anti-TES antibodies

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Mouse Anti-TES Recombinant Antibody (CBYJT-2555) (CBMAB-T1713-YJ)

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Target: TES

Host: Mouse

Antibody Isotype: IgG1, κ

Specificity: Human

Clone: CBYJT-2555

Application*: E, IF, IH, WB

Mouse Anti-TES Recombinant Antibody (1G11-B7) (CBMAB-A9013-LY)

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Target: TES

Host: Mouse

Antibody Isotype: IgG1, κ

Specificity: Human

Clone: 1G11-B7

Application*: WB, E

Mouse Anti-TES Recombinant Antibody (CBYJT-2554) (CBMAB-T1712-YJ)

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Target: TES

Host: Mouse

Antibody Isotype: IgG1, κ

Specificity: Human

Clone: CBYJT-2554

Application*: E, WB, P, IF, IC

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Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized)

Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)

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Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized)

Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)

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For Research Use Only. Not For Clinical Use.

(P): Predicted

* Abbreviations

AActivation
AGAgonist
APApoptosis
BBlocking
BABioassay
BIBioimaging
CImmunohistochemistry-Frozen Sections
CIChromatin Immunoprecipitation
CTCytotoxicity
CSCostimulation
DDepletion
DBDot Blot

EELISA
ECELISA(Cap)
EDELISA(Det)
ESELISpot
EMElectron Microscopy
FFlow Cytometry
FNFunction Assay
GSGel Supershift
IInhibition
IAEnzyme Immunoassay
ICImmunocytochemistry
IDImmunodiffusion
IEImmunoelectrophoresis

IFImmunofluorescence
IGImmunochromatography
IHImmunohistochemistry
IMImmunomicroscopy
IOImmunoassay
IPImmunoprecipitation
ISIntracellular Staining for Flow Cytometry
LALuminex Assay
LFLateral Flow Immunoassay
MMicroarray
MCMass Cytometry/CyTOF
MDMeDIP

MSElectrophoretic Mobility Shift Assay
NNeutralization
PImmunohistologyp-Paraffin Sections
PAPeptide Array
PEPeptide ELISA
PLProximity Ligation Assay
RRadioimmunoassay
SStimulation
SESandwich ELISA
SHIn situ hybridization
TCTissue Culture
WBWestern Blot

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